Results 121 to 130 of about 665,264 (303)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Self assessment: revenue authorities v. taxpayers: a state of conflict?
, 1999 THE purpose of this article is to examine the change in our tax system to self assessment, discussing whether it moves us closer to an “ideal” tax system thereby reducing conflict in the relationship between taxpayer and ...
Teviotdale, Wilma, Thompson, Susan
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Work-Family Conflict and Facilitation among Employees in Hong Kong
, 2014 Work-family imbalance can induce negative consequences, such as poor physical and psychological well-being for individuals. Hong Kong employees commonly agree that work-family balance is important for them, but it is difficult to balance work and family
Wong, Chi Kin
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
BBC TV's Panorama, conflict coverage and the 'Westminster consensus'.
The BBC's 'flagship' current affairs series Panorama, occupies a central place in Britain's television history and yet, surprisingly, it is relatively neglected in academic studies of the medium.
McQueen, David
core
Assurance of corporate stand-alone reporting : evidence from the UK
, 2008 Since the early 1990’s the number of corporate stand-alone reports produced by various organisations worldwide has increased considerably (Kolk, 2004; Owen, 2006).
Al-Hamadeen, Radhi Mousa
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Reporting violent conflict in Kwazulu-Natal: an assessment of selected sources for conflict research. [PDF]
, 1995 Thesis (M.A.)-University of Natal, Durban, 1995.The main aim of this study was to investigate which factors are likely to affect the probability that events of violent collective action are reported by the press in KwaZulu-Natal. The study hypothesised
Louw, Antoinette.
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source