Results 181 to 190 of about 2,495,805 (292)

Assessment of the electoral framework : Sudan / Democracy Reporting

, 2009
unknown
core   +1 more source

Impact of the 2023-armed conflict on routine malaria imapact indicators in Sudan (January 2020-March 2025): a mixed-methods analysis of surveillance data. [PDF]

Malar J
Alnaeem KF, Saha UR, Ahmed HF, Mergenthaler C.   +3 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Assessment of pharmacy professionals' workplace satisfaction in a conflict-affected health system: evidence from Yemen. [PDF]

J Pharm Policy Pract
Hatem NAH.
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Comprehensive assessment of election framework : Yemen / Democracy Reporting

, 2008
unknown
core   +1 more source

Enteral nutrition intolerance: Evidence mapping of definitions and assessment practices to inform future gastric cancer-specific assessment tool development. [PDF]

Asia Pac J Clin Nutr
Fu W, Xu Q, Zhang R, Liu C, Wang X.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Evaluation du cadre pour l'organisation des élections / Democracy Reporting International

, 2007
unknown
core   +1 more source

Emerging hotspots of groundwater conflicts during droughts in Germany. [PDF]

iScience
Sodoge J, Kuhlicke C, Di Baldassarre G, Fleckenstein JH, Ebeling P, Madruga de Brito M.   +5 more
europepmc   +1 more source