Results 131 to 140 of about 1,787,762 (305)

Remove-Win: a Design Framework for Conflict-free Replicated Data Collections

open access: yes, 2019
Internet-scale distributed systems often replicate data within and across data centers to provide low latency and high availability despite node and network failures.
Huang, Yu   +3 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Smart and Dangerous: How Cognitive Skills Drive the Intergenerational Transmission of Retaliation [PDF]

open access: yes
A need exists to understand how people develop an aggressive, retaliatory conflict resolution policy vs. a more passive reconciliation stance. I contribute a choice-theoretic model that explains how cognitive skills drive the transmission of conflict ...
Henry, Ruby
core  

Conflict Resolution Concept: Implementation of Cca-fm Model in Meranti Forest Management Unit, South Sumatra [PDF]

open access: yes, 2018
Local communities have been using forest land area far before Industrial Forest Plantation (HTI) permit was granted. The overlapping land use among different users potentially leads to conflict.
Basuni, S. (Sambas)   +3 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Contemporary Conflict Resolution and Islamic Conflict Resolution: Similarity and Differentiation on the Theoretical Level [PDF]

open access: yes, 2014
The critiques towards Cosmopolitan conflict resolution theory that it cannot be applied universally because it is incompatible with the characteristics of the conflict in the other part of the world beyond Western significantly influence the field ...
Sabban, N. (Nabilla)
core  

Balancing risk and reward: exploring women’s transactional sexual relationships with Blessers in South Africa

open access: yesHumanities & Social Sciences Communications
Transactional sexual relationships (TSRs) take varied forms, with research emphasizing TSRs’ inherent risks, primarily to women. In South Africa, Blessed relationships have emerged as a prominent type of TSR.
Gavin George   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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