Results 71 to 80 of about 3,078,842 (218)

Processus territoriaux et gestion de l’eau en Camargue gardoise

Développement Durable et Territoires, 2013
Next to the major changes which occurred in the « Camargue gardoise » during sixties and seventies, and because of the becoming obsolete « Traité des Marais » which was regulating the collective management of water levels, the economic actors dealing ...
Daniel Petit, Anne Rivière-Honegger
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Understanding stakeholders' perspectives behind wildfires in Sicily: A Q‐methodology approach

People and Nature
Mediterranean wildfires persistently challenge regions due to climatic factors, changing land use, and abandonment of rural areas, posing threats to both ecosystems and human well‐being.
Erika Piroli, Donato Salvatore La Mela Veca, Jay Mistry, Yiannis Kountouris   +3 more
doaj   +1 more source

“Geopolitical Geometry” in the Works of E.M. Primakov

Современная наука и инновации
According to leading Russian analysts, the professional activity of E.M. Primakov in the most important government posts is a benchmark for subsequent generations of politicians and diplomats.
P. L. Karabushenko
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Influence of School Culture and Organizational Culture on Conflicts: Case of Serbian Primary Schools

Education Sciences
This paper explores how school culture and key organizational culture dimensions, power distance, humane orientation, performance orientation, and in-group collectivism, affect different types of conflict (task, relationship, and process) in primary ...
Igor Kostovski, Dragana Glušac, Srđana Taboroši, Edit Terek Stojanović, Branka Janković, Milan Nikolić   +5 more
doaj   +1 more source