Results 111 to 120 of about 12,516 (241)

Unveiling a BRAF Signature Proficient in Accurately Capturing Oncogenic Activity and Guiding Prognostic Prediction Across Multiple Cancers

open access: yesMedComm, Volume 7, Issue 2, February 2026.
The BRAF25 meta‐signature effectively captures BRAF‐driven oncogenic activity. By enabling precise patient stratification with distinct mutation profiles, BRAF25 identifies BRAF‐active tumor subtypes and provides superior prognostic value compared with mutation status alone.
Kaidi Yang   +7 more
wiley   +1 more source

Self-Similar Solutions of a Multidimensional Degenerate Partial Differential Equation of the Third Order

open access: yesMathematics
When studying the boundary value problems’ solvability for some partial differential equations encountered in applied mathematics, we frequently need to create systems of partial differential equations and explicitly construct linearly independent ...
Ainur Ryskan   +3 more
doaj   +1 more source

INTEGRALS OF CONFLUENT HYPERGEOMETRIC FUNCTIONS

open access: yesTamkang Journal of Mathematics, 1990
The moments of the weight functions $w(x)=e^{-x}x^\mu(\ln x)^\rho$, $\rho=0, 1, 2$, on $[0, \infty)$ with respect to the Confluent Hypergeometric function $\phi(a - n, c;x)$, $n = 0, 1, 2, \cdots$, are explicitly evaluated.
openaire   +2 more sources

Spectral Parameter Power Series Representation for Regular Solutions of the Radial Dirac System

open access: yesMathematical Methods in the Applied Sciences, Volume 49, Issue 3, Page 2098-2113, February 2026.
ABSTRACT A spectral parameter power series (SPPS) representation for the regular solution of the radial Dirac system with complex coefficients is obtained, as well as a SPPS representation for the (entire) characteristic function of the corresponding spectral problem on a finite interval. Based on the SPPS representation, a numerical method for solving
Emmanuel Roque, Sergii M. Torba
wiley   +1 more source

RCC1 Domain‐Containing Protein 1 Promotes Colon Cancer Malignant Progression by Activating Autophagy‐Dependent WNT5A Secretion in Cancer‐Associated Fibroblasts

open access: yesJournal of the Royal Society of New Zealand, Volume 56, Issue 1, February 2026.
RCCD1 is upregulated in colon cancer and cancer‐associated fibroblasts (CAFs). In CAFs, RCCD1 overexpression activates AMPK/mTOR/ULK1 signaling, enhancing autophagy. This stimulates autophagic secretion of WNT5A. WNT5A then activates the nonclassical Wnt/CaMKII/ERK pathway in tumor cells, promoting epithelial‐mesenchymal transition (EMT), proliferation,
Chao Liu   +3 more
wiley   +1 more source

The Role of the Gut Microbiome in the Complex Network of Frailty Syndrome and Associated Comorbidities in Aging

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
This study analyzed gut microbiota in older adults with and without Frailty Syndrome by 16S rRNA gene sequencing and metagenomics. Frailty was associated with altered microbial composition, metabolic functions, and increased antimicrobial resistance, whereas non‐frail individuals showed healthier profiles.
Ana Barberá   +5 more
wiley   +1 more source

Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes

open access: yesAndrology, Volume 14, Issue 2, Page 528-544, February 2026.
ABSTRACT Background Epidemiological studies have reported an association between advanced paternal age at conception and an increased risk of neurodevelopmental disorders in offspring, such as autism spectrum disorder. Evidence suggests that DNA methylation alterations in spermatozoa of older men may be transmitted to the feto‐placental unit and ...
Julia Barnwell   +12 more
wiley   +1 more source

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