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Immunology and the confocal microscope
Research in Immunology, 1996The techniques of classical epifluorescence microscopy are already widely used by the immunological community to detect antigens at the cellular level. Coupled with the use of specific inhibitors that affect diverse intracellular events, these techniques have provided valuable information on the mechanisms involved in antigen presentation.
Agathe Subtil +5 more
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Measurement in the Confocal Microscope
2003All measurements require that the microscope must be aligned as accurately as possible, and the gain (or PMT voltage) and black level must be set to avoid any overflow or underflow. Measuring surface profiles and relative depths is straightforward and can be carried out to a higher accuracy than the depth resolution of the microscopes, even though the ...
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Mathematical Notes, 1932
In the standard text books on Analytical Geometry the following problem occurs in the exercises on confocals:The product of the four normals from a point P to the ellipseX2/a2 + Y2/b2 = 1 is equal to where λ1 and λ2 are the parameters of the confocals through P.
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In the standard text books on Analytical Geometry the following problem occurs in the exercises on confocals:The product of the four normals from a point P to the ellipseX2/a2 + Y2/b2 = 1 is equal to where λ1 and λ2 are the parameters of the confocals through P.
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Journal of Microscopy, 1992
SUMMARYThe confocal‐line (CL) technique combines some of the characteristics of confocal‐scanning microscopy with those of conventional‐imaging methods. It is based on the introduction of line‐shaped illumination and linear image detection, as an alternative to the current confocal‐point (CP) approach.
D. Guidarini +3 more
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SUMMARYThe confocal‐line (CL) technique combines some of the characteristics of confocal‐scanning microscopy with those of conventional‐imaging methods. It is based on the introduction of line‐shaped illumination and linear image detection, as an alternative to the current confocal‐point (CP) approach.
D. Guidarini +3 more
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Endoscopic confocal microscopy
Current Opinion in Gastroenterology, 2005Endoscopic confocal microscopy is a new endoscopic imaging technology that produces high-magnification cross-sectional images of the gastrointestinal epithelium during endoscopy. These high-magnification images might allow the endoscopist to make a tissue diagnosis during endoscopy without biopsy and histopathology.
John A. Evans, Norman S. Nishioka
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Applied Optics, 1993
A confocal image slicer for use in high-resolution spectrography in astrophysics is presented. The deviceimproves the light transmission of a high-resolution spectrograph by an (unprecedented) order of magnitude. The production of a prototype is described, and the first astronomical results obtained with the Anglo-Australian Telescope are presented ...
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A confocal image slicer for use in high-resolution spectrography in astrophysics is presented. The deviceimproves the light transmission of a high-resolution spectrograph by an (unprecedented) order of magnitude. The production of a prototype is described, and the first astronomical results obtained with the Anglo-Australian Telescope are presented ...
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Confocal spectroscopy in microstructures
Biophysical Chemistry, 1997Confocal instrumentation makes it possible to carry out spectroscopic measurements with a very high signal-to-background ratio. The transit of a single fluorescent molecule through the focal point of the light can be monitored with this method. The particle transport can be observed in transparent microchannels.
Rudolf Rigler +3 more
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Trends in Neurosciences, 1989
Abstract Confocal microscopy is a relatively new technique that permits us to obtain high-resolution images of very thin sections of a specimen. This unique optical sectioning property, together with a suitable computer, allows us to image structures in three dimensions.
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Abstract Confocal microscopy is a relatively new technique that permits us to obtain high-resolution images of very thin sections of a specimen. This unique optical sectioning property, together with a suitable computer, allows us to image structures in three dimensions.
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Current Opinion in Ophthalmology, 1998
Because it provides much higher magnification and better optical sectioning than a slit-lamp biomicroscope, confocal microscopy is ideally suited for clinical imaging of the cornea. One important clinical application of confocal microscopy has been the early detection and diagnosis of a number of infectious conditions, including infection with ...
Harrison D Cavanagh +2 more
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Because it provides much higher magnification and better optical sectioning than a slit-lamp biomicroscope, confocal microscopy is ideally suited for clinical imaging of the cornea. One important clinical application of confocal microscopy has been the early detection and diagnosis of a number of infectious conditions, including infection with ...
Harrison D Cavanagh +2 more
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The European Physical Journal Plus, 2012
Modern biomedical research is currently dominated by imaging and measuring with optical microscopes. One branch of the microscopy technology is confocal microscopy. For correlation purposes, multiparameter fluorescence imaging is particularly of unique interest.
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Modern biomedical research is currently dominated by imaging and measuring with optical microscopes. One branch of the microscopy technology is confocal microscopy. For correlation purposes, multiparameter fluorescence imaging is particularly of unique interest.
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