Results 121 to 130 of about 2,536,050 (286)

Macrophage–Fibroblast Crosstalk Governs Tumor Mechanics, as Revealed by Spatiotemporal Force Mapping in 3D Spheroids

open access: yesAdvanced Healthcare Materials, EarlyView.
This study shows crosstalk among tumor cells, fibroblasts, and macrophages alters the physical forces inside 3D tumor spheroids. Incorporating deformable microparticles in 3D tumor spheroids, the researchers mapped mechanical stresses spatially and with respect to tumor growth (temporally).
Kunal P. Pednekar   +2 more
wiley   +1 more source

Permeability changes of the cell-contained microcapsules visualized by confocal laser scanning microscope

open access: yes, 2009
Microencapsulation of recombinant cells is a novel means for gene therapy. However, one of the major concerns is the relationship between the permeability of microcapsule and cell growth.
Lv, Guojun   +10 more
core   +1 more source

The Role of Viscoelasticity in Heterogeneous Glioblastoma Stem Cell Invasion in Biomimetic 3‐Dimensional Hydrogels

open access: yesAdvanced Healthcare Materials, EarlyView.
The role of viscoelasticity in the invasion of heterogeneous glioblastoma stem cells (GSCs) was investigated with GSCs categorized into subgroups based on molecular profile, as Reactive, Invasive, or Constructive using viscoelastic biomimetic hyaluronan‐oxime hydrogels.
Nicole J. Blaine   +4 more
wiley   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez   +12 more
wiley   +1 more source

Влияние меди на цитоскелет разных типов клеток корней Arabidopsis thaliana

open access: yesФактори експериментальної еволюції організмів, 2015
Aims. Copper (Cu) is a micronutrient that has roles in photosynthesis, respiration, antioxidant activity, cell wall metabolism and hormone perception. Excess Cu is toxic and therefore its delivery has to be tightly regulated. Methods.
И. И. Горюнова   +1 more
doaj  

Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers

open access: yesAdvanced Healthcare Materials, EarlyView.
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li   +9 more
wiley   +1 more source

Observation of Pseudomonas aeruginosa Biofilm with Confocal Laser Scanning Microscope

open access: yesJournal of the Japanese Association for Infectious Diseases, 1995
Confocal laser scanning microscope (CLSM) is a new type of microscope, which permits non-invasive optical sectioning of biomaterials by reducing out-of-focus haze. A biofilm of Pseudomonas aeruginosa was developed on the silicon disks using a modified Robbins device and used to visualize hydrated living biofilm with CLSM.
openaire   +3 more sources

Biofilm analysis by confocal laser scanning microscope.

open access: yes, 2012
S. mutans biofilms were grown anaerobically on hydroxylapatite discs in 12-well plates in BM medium supplemented with 10 mM sucrose for 48 hours. Following proper staining using LIVE/DEAD BacLight fluorescent dye, biofilms were subjected to optical ...
Zezhang T. Wen (135862)   +4 more
core   +1 more source

Pressure‐Assisted Drug Delivery Using High‐Pressure Balloon Platform Improves Vascular Drug Penetration and Anti‐Restenotic Effects

open access: yesAdvanced Healthcare Materials, EarlyView.
A dual‐layer high‐pressure drug‐coated balloon (HP@DCB) increased balloon‐wall contact and promoted deeper paclitaxel (PTX) penetration than a conventional noncompliant DCB. In in vivo study, HP@DCB treatment improved luminal patency and reduced neointimal hyperplasia, supporting pressure‐assisted drug delivery as a promising strategy for enhancing the
Seung Jin Eo   +10 more
wiley   +1 more source

Development of a Reflection-type Ultraviolet Laser Scanning Confocal Microscope Combined with an Atomic Force Microscope

open access: yes, 2011
The construction and the application of a reflection-type ultraviolet laser scanning confocal microscope combined with an atomic force microscope for simultaneous measurement of optical and topographical characteristics of photonic nanostructures are ...
Hyun Jeong   +9 more
core   +1 more source

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