This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang +13 more
wiley +1 more source
Comparative evaluation of three different methods of surface pretreatment on the depth of adhesive resin penetration in sandwich technique - An <i>in vitro</i> confocal laser scanning microscopy study. [PDF]
Kunhappan S +5 more
europepmc +1 more source
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang +15 more
wiley +1 more source
Evaluation the impact of access cavity design and activation of calcium silicate-based sealer with EDDY and XP-Endo Finisher on sealer penetration into dentinal tubules: a confocal laser scanning microscopy study. [PDF]
Sarı M, Tüfenkçi P.
europepmc +1 more source
This study explores the use of N, S co‐doped carbon quantum dots (NS‐CQDs) as carriers for riboflavin, creating NS‐CQDs‐RF composite photosensitizers. These composites improve riboflavin absorption, enhance ROS generation efficiency, and preserve corneal epithelium integrity.
Tinghong Xu +9 more
wiley +1 more source
Evaluating the penetration efficacy of calcium silicate-based bioceramic sealers into dentinal tubules with cold lateral compaction technique using confocal laser scanning microscopy: An <i>in vitro</i> study. [PDF]
Mann NS, Mann NK, Kapur R.
europepmc +1 more source
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia +17 more
wiley +1 more source
Impact of different activation procedures on sodium hypochlorite penetration into dentinal tubules after endodontic retreatment via confocal laser scanning microscopy. [PDF]
Gunes B, Yeter KY, Altay Y.
europepmc +1 more source

