Results 251 to 260 of about 44,660 (298)

Quantification of microparticle coating quality by confocal laser scanning microscopy (CLSM)

European Journal of Pharmaceutics and Biopharmaceutics, 2009
In this work, a novel protocol was developed for determining film coating thickness and coating quality of microparticles, based on the use of confocal laser scanning microscopy (CLSM). CLSM was found to be an adequate non-destructive technique for the quantification of the coating thickness and coating quality of individual thin-coated small particles.
F, Depypere, P, Van Oostveldt, J G, Pieters, K, Dewettinck   +3 more
openaire   +4 more sources

Visualization and quantification of polymer distribution in microcapsules by confocal laser scanning microscopy (CLSM)

International Journal of Pharmaceutics, 2000
Confocal laser scanning microscopy (CLSM) was employed in order to characterize microcapsules. Microcapsules were prepared by complex coacervation: gelatin and arabic gum were labelled with fluorescent markers. In the capsule wall a homogeneous distribution for both gelatin and arabic gum throughout the capsule wall was depicted. By the use of CLSM and
A, Lamprecht, U F, Schäfer, C M, Lehr
openaire   +4 more sources

Combined use of confocal laser scanning microscopy (CLSM) and Raman microscopy (RM): Investigations on EPS – Matrix

Water Research, 2009
Confocal laser scanning microscopy (CLSM) was applied in combination with Raman microscopy (RM) for the characterization of heterotrophic biofilms. Compared to CLSM, RM allows for a deeper insight into the chemical structure of extracellular polymeric substances (EPS) of the biofilm matrix.
Michael, Wagner, Natalia P, Ivleva, Christoph, Haisch, Reinhard, Niessner, Harald, Horn   +4 more
openaire   +4 more sources

Optically sliced micro-PIV using confocal laser scanning microscopy (CLSM)

Experiments in Fluids, 2004
Optically sliced microscopic-particle image velocimetry (micro-PIV) is developed using confocal laser scanning microscopy (CLSM). The developed PIV system shows a unique optical slicing capability allowing true depth-wise resolved micro-PIV vector field mapping. A comparative study between CLSM micro-PIV and con- ventional epi-fluorescence micro-PIV is
Jae Sung Park, Chang Kyoung Choi, Kenneth D. Kihm   +2 more
openaire   +3 more sources

Use of confocal laser scanning microscopy (CLSM) for depthwise resolved microscale-particle image velocimetry (μ-PIV)

Optics and Lasers in Engineering, 2006
A novel use of confocal laser scanning microscopy (CLSM) makes the truly focused field-of-view with well-defined depthwise resolution possible for microscale particle image velocimetry (μ-PIV) applications. The operating principle of the CLSM is presented using the point spread function (PSF) that describes diffracted images of extremely small ...
J.S. Park, K.D. Kihm
openaire   +3 more sources

Confocal Laser Scanning Microscopy (CLSM), A Tool for Counterfeit Detection

International Symposium for Testing and Failure Analysis, 2018
Abstract This paper explains the CLSM technique and presents surface roughness measurement data from several groups of known authentic and suspect counterfeit parts. Surface roughness is an important characteristic of plastic encapsulated or metal lidded parts because counterfeit parts are often blacktopped or re-polished and remarked.
M. Simard-Normandin, R. Rahman
openaire   +1 more source

Confocal laser scanning microscopy (CLSM) for the study of collagen sponge microstructure

Journal of Biomedical Materials Research, 1994
AbstractThis study uses confocal laser scanning microscopy (CLSM) to assess the microstructure of collagen sponges providing an accurate quantification of porosity under conditions similar to those experienced by cells growing on the sponges during culture.
M, Hanthamrongwit, M H, Grant, R, Wilkinson   +2 more
openaire   +2 more sources

Quantitative Fluorescence Confocal Laser Scanning Microscopy (CLSM)

1995
The confocal imaging geometry provides a dramatic optical advantage for fluorescence microscopy by discriminating against out-of-focus background with minimal loss of image-forming signal. Significant enhancement of both axial and lateral imaging resolution is also available but only with substantial signal loss.
David R. Sandison, Rebecca M. Williams, K. Sam Wells, James Strickler, Watt W. Webb   +4 more
openaire   +1 more source

DNA‐FLUORESCENCE OF MAMMALIAN INTRA‐NUCLEOLAR CHROMATIN DETECTED BY CONFOCAL LASER SCANNING MICROSCOPY (CLSM)

Biology of the Cell, 1988
The complex spatial DNA distribution in the mammalian interphase nucleus was investigated in Feulgen stained thick sections through mouse trophoblast giant nuclei after Lowicryl embedding. DNA‐fluorescence was visualized using confocal laser scanning microscopy.
H, Spring, M F, Trendelenburg, M, Montag
openaire   +2 more sources

Characterization of theGeosiphon pyriforme symbiosome by affinity techniques: confocal laser scanning microscopy (CLSM) and electron microscopy

Protoplasma, 1996
Geosiphon pyriforme represents a photoautotrophic endosymbiosis of aGlomus-like fungus with the cyanobacteriumNostoc punctiforme. The fungus forms unicellular bladders of up to 2 mm in length and 0.5 mm in diameter growing on the soil surface and harboring the endosymbioticNostoc filaments. The cyanobacteria are located in a compartment (the symbiosome)
A. Schussler, BONFANTE, Paola, E. Schnepf, D. Mollenhauer, M. Kluge   +4 more
openaire   +1 more source