Results 1 to 10 of about 236,330 (149)

Confocal Raman Spectroscopy for Assessing Bioequivalence of Topical Formulations

open access: yesPharmaceutics, 2023
The evaluation of bioequivalence (BE) for topical dermatological drug products is challenging, and there has been significant interest from regulatory authorities in developing new BE methodologies in recent years.
Fotis Iliopoulos   +4 more
doaj   +7 more sources

Inflammation and fibrosis in the coal dust-exposed lung described by confocal Raman spectroscopy [PDF]

open access: yesPeerJ, 2022
Background Coal workers’ pneumoconiosis (CWP) is an occupational disease that severely damages the life and health of miners. However, little is known about the molecular and cellular mechanisms changes associated with lung inflammation and fibrosis ...
Wenyang Wang   +6 more
doaj   +3 more sources

Interfacial Stress Characterization of GaN Epitaxial Layer With Sapphire Substrate by Confocal Raman Spectroscopy

open access: yesNami Jishu Yu Jingmi Gongcheng/Nanotechnology and Precision Engineering, 2021
As an important wide-bandgap semiconductor, gallium nitride (GaN) has attracted considerable attention. This paper describes the use of confocal Raman spectroscopy to characterize undoped GaN, n-type GaN, and p-type GaN through depth profiling using 405-,
Zongwei Xu, Bing Dong
exaly   +2 more sources

Detection and Classification of Multi-Type Cells by Using Confocal Raman Spectroscopy

open access: yesFrontiers in Chemistry, 2021
Tumor cells circulating in the peripheral blood are the prime cause of cancer metastasis and death, thus the identification and discrimination of these rare cells are crucial in the diagnostic of cancer. As a label-free detection method without invasion,
Jing Wen   +7 more
doaj   +2 more sources

Machine Learning Assisted Handheld Confocal Raman Micro-Spectroscopy for Identification of Clinically Relevant Atopic Eczema Biomarkers

open access: yesSensors, 2022
Atopic dermatitis (AD) is a common chronic inflammatory skin dermatosis condition due to skin barrier dysfunction that causes itchy, red, swollen, and cracked skin.
Kapil Dev   +8 more
doaj   +2 more sources

Depth Profiling of Ion-Implanted 4H–SiC Using Confocal Raman Spectroscopy

open access: yesCrystals, 2020
For silicon carbide (SiC) processed by ion-implantation, dedicated test structure fabrication or destructive sample processing on test wafers are usually required to obtain depth profiles of electrical characteristics such as carrier concentration.
Ying Song   +6 more
doaj   +2 more sources

In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy

open access: yesNature Communications, 2020
Raman spectroscopic imaging (RSI) can provide information on the chemical composition of a sample, but application to living organisms has lacked sufficient spatial resolution and signal strength.
Håkon Høgset   +10 more
doaj   +2 more sources

Franz Cell Diffusion Testing and Quantitative Confocal Raman Spectroscopy: In Vitro-In Vivo Correlation

open access: yesPharmaceutics, 2020
Previously, we reported the use of Confocal Raman Spectroscopy (CRS) to investigate the topical delivery of actives and excipients. We have also correlated the results from CRS with findings from in vitro diffusion studies in human skin.
Gerwin Puppels   +2 more
exaly   +2 more sources

Conformation Changes in Human Hair Keratin Observed Using Confocal Raman Spectroscopy After Active Ingredient Application

open access: yesInternational Journal of Cosmetic Science, 2019
In hair care cosmetic products’ evaluation, one commonly used method is to evaluate the hair appearance as a gold standard in order to determine the effect of an active ingredient on the final state of the hair via visual appreciation.
Gobinet Cyril, Marie Meunier, M Manfait
exaly   +2 more sources

In vivo confocal Raman spectroscopy for intrinsic aging and photoaging assessment. [PDF]

open access: yesJournal of Dermatological Science, 2017
In vivo confocal Raman spectroscopy is a non-invasive method to assess either the epidermis or the dermis composition. Few studies have focused on dermis collagen alterations through intrinsic aging and photoaging.This study evaluated the in vivo Raman spectra from the dermis of a photoexposed site versus a non-photoexposed region in different age ...
L. de Vasconcelos Nasser Caetano   +6 more
semanticscholar   +4 more sources

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