Confocal Raman Spectroscopy for Assessing Bioequivalence of Topical Formulations [PDF]
The evaluation of bioequivalence (BE) for topical dermatological drug products is challenging, and there has been significant interest from regulatory authorities in developing new BE methodologies in recent years.
Fotis Iliopoulos +4 more
doaj +7 more sources
Inflammation and fibrosis in the coal dust-exposed lung described by confocal Raman spectroscopy [PDF]
Background Coal workers’ pneumoconiosis (CWP) is an occupational disease that severely damages the life and health of miners. However, little is known about the molecular and cellular mechanisms changes associated with lung inflammation and fibrosis ...
Wenyang Wang +6 more
doaj +3 more sources
Detection and Classification of Multi-Type Cells by Using Confocal Raman Spectroscopy [PDF]
Tumor cells circulating in the peripheral blood are the prime cause of cancer metastasis and death, thus the identification and discrimination of these rare cells are crucial in the diagnostic of cancer. As a label-free detection method without invasion,
Jing Wen +7 more
doaj +2 more sources
In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy [PDF]
Raman spectroscopic imaging (RSI) can provide information on the chemical composition of a sample, but application to living organisms has lacked sufficient spatial resolution and signal strength.
Håkon Høgset +10 more
doaj +2 more sources
Evaluation of the In Vivo Skin Penetration of TXVector by Confocal Raman Spectroscopy. [PDF]
ABSTRACT Background Tranexamic acid (TXA) is a promising active to treat hyperpigmentation disorders, such as melasma and acne scars. However, TXA is highly hydrophilic and its penetration into the skin is poor and formulation dependent.
Winn D +4 more
europepmc +4 more sources
Confocal Raman microspectroscopy for spatially resolved tissue characterisation of disease‐linked spectra‐pathological signatures [PDF]
Raman spectroscopy is a versatile analytical technique for highly specific molecular characterisation of cells, biofluids and tissues. Confocal Raman microspectroscopy combines optical microscopy with Raman spectroscopy to spatially resolve biochemical ...
Nektarios A. Valous +2 more
doaj +2 more sources
Lymph node study by confocal Raman spectroscopy
Among the lymphoid organs there are lymph nodes,, which are considered as lymph filters because they are rich in lymphocytes and other defense cells.
Juliana dos Santos Corrêa +6 more
doaj +1 more source
Franz Cell Diffusion Testing and Quantitative Confocal Raman Spectroscopy: In Vitro-In Vivo Correlation [PDF]
Fotis Iliopoulos +2 more
exaly +2 more sources
Conformation changes in human hair keratin observed using confocal Raman spectroscopy after active ingredient application [PDF]
M Meunier +2 more
exaly +2 more sources
Noise Sources and Requirements for Confocal Raman Spectrometers in Biosensor Applications
Raman spectroscopy probes the biochemical composition of samples in a non-destructive, non-invasive and label-free fashion yielding specific information on a molecular level. Nevertheless, the Raman effect is very weak. The detection of all inelastically
Izabella J. Jahn +5 more
doaj +1 more source

