Results 51 to 60 of about 1,815 (296)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

The Limited Validity of the Conformable Euler Finite Difference Method and an Alternate Definition of the Conformable Fractional Derivative to Justify Modification of the Method

, 2021
A method recently advanced as the conformable Euler method (CEM) for the finite difference discretization of fractional initial value problem Dtαyt = ft;yt, yt0 = y0, a≤t≤b, and used to describe hyperchaos in a financial market model, is shown to be ...
Dominic Clemence-Mkhope, Belinda Clemence-Mkhope   +1 more
core   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

A new conformable nabla derivative and its application on arbitrary time scales

Advances in Difference Equations, 2021
In this article, we introduce a new type of conformable derivative and integral which involve the time scale power function G ˆ η ( t , a ) $\widehat{\mathcal{G}}_{\eta }(t, a)$ for t , a ∈ T $t,a\in \mathbb{T}$ .
Mohamad Rafi Segi Rahmat, M. Salmi M. Noorani   +1 more
doaj   +1 more source

Higher-order time-fractional Sasa–Satsuma equation: Various optical soliton solutions in optical fiber

Results in Physics, 2023
In this paper, the generalized (3+1)-dimensional nonlinear Sasa–Satsuma model with conformable fractional derivative using the new Kudryashov approach is considered to find a class of novel exact solutions in optical fibers.
Muhammad Amin S. Murad, Hajar F. Ismael, Tukur A. Sulaiman, Nehad A. Shah, Jae Dong Chung   +4 more
doaj   +1 more source

Frenet frame with respect to conformable derivative

Filomat, 2019
Conformable fractional derivative is introduced by the authors Khalil at al in 2014. In this study, we investigate the frenet frame with respect to conformable fractional derivative. Curvature and torsion of a conformable curve are defined and the geometric interpretation of these two functions is studied.
Gozutok, Ugur, Coban, Husnu Anil, Sagiroglu, Yasemin   +2 more
openaire   +4 more sources

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Exact solutions of fractional partial differential equation systems with conformable derivative

, 2019
Main goal of this paper is to have the new exact solutions of some fractional partial differential equation systems (FPDES) in conformable sense. The definition of conformable fractional derivative (CFD) is similar to the limit based definition of known ...
Özkan, O., Özkan, Ozan., Kurt, Ali, Kurt, Ali.   +3 more
core   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source