Results 221 to 230 of about 37,668 (284)

Identification and Biological Characterization of a Novel NRF2 Activator Molecule Released From the Membranes of Heat‐Treated Bifidobacterium breve NCC 2950

open access: yesMolecular Nutrition &Food Research, EarlyView.
We have shed light on the mode of action behind the postbiotic form of Bifidobacterium breve NCC 2950. Heat treatment of this strain at 90°C leads to the production of 4‐oxo‐2‐pentenoic acid (OPA), which activates NRF2 host response, improving oxidative stress resistance and decreasing inflammation. ABSTRACT Postbiotics are defined as a “preparation of
Francis Foata   +11 more
wiley   +1 more source

Applications of Elzaki transform to non-conformable fractional derivatives

open access: gold
Shams A. Ahmed   +5 more
openalex   +1 more source

Proteomic Profiling Informs Mechanisms of Esophageal Adenocarcinoma Inhibition by Cranberry Proanthocyanidins

open access: yesMolecular Nutrition &Food Research, EarlyView.
In this study we utilized proteomic profiling to investigate mechanisms linked to the cancer‐inhibitory effect of cranberry proanthocyanidins (CPACs) on reflux‐induced esophageal adenocarcinoma in a rat model. The results indicate that CPAC inhibits cancer through targeting multiple hallmarks of cancer known to be dysregulated in progression to ...
Yun Zhang   +7 more
wiley   +1 more source

Breast Cancer: Habitat imaging based on intravoxel incoherent motion for predicting pathologic complete response to neoadjuvant chemotherapy

open access: yesMedical Physics, EarlyView.
Abstract Background Radiomics research based on whole tumors is limited by the unclear biological significance of radiomics features, which therefore lack clinical interpretability. Purpose We aimed to determine whether features extracted from subregions defined by habitat imaging, reflecting tumor heterogeneity, could identify breast cancer patients ...
Hui Zhang   +8 more
wiley   +1 more source

Solving Large‐Scale Weapon Target Assignment Problems in Seconds Using Branch‐Price‐And‐Cut

open access: yesNaval Research Logistics (NRL), EarlyView.
ABSTRACT This paper proposes a framework based on branch‐price‐and‐cut to solve the weapon target assignment (WTA) problem, a popular class of non‐linear assignment problems that has received significant attention over the past several decades. We first reformulate the WTA into a form amenable to column generation and then derive efficient algorithms ...
Dimitris Bertsimas, Alex Paskov
wiley   +1 more source

A robust stability criterion in the heat equation with a conformable fractional derivative defined on a radially symmetric sphere

open access: diamond
Raúl Temoltzi-Ávila   +4 more
openalex   +1 more source

Aqueous/Nonaqueous DBU Mixtures: Versatile Switching Media for Chemoselective Aldol, Baylis‐Hillman, and Aldol Condensation Reactions

open access: yesChemistryOpen, EarlyView.
A switchable DBU‐catalyzed procedure is designed for the reaction of isophorone with aldehydes to give either aldol, Baylis‐Hillman, or aldol condensation products, depending on the use of water and/or heat. The observed divergency stems from the ability to tune the dual nucleophilicity/basicity characters of the medium. The conditions are amenable for
Elaheh Akbarzadeh   +5 more
wiley   +1 more source

Treatment of Intermediate‐Risk Hepatoblastoma Using a Combined Cisplatin and Doxorubicin (PLADO) Regimen and Optimized Surgical Resection

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Complete resection of the primary tumor is critical for the survival of children with hepatoblastomas (HBs). This prospective clinical study aimed to clarify the outcome of a chemotherapy regimen comprising cisplatin and doxorubicin (PLADO) followed by definitive surgery conducted at the appropriate time in patients with ...
Tomoro Hishiki   +25 more
wiley   +1 more source

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