Results 41 to 50 of about 1,275 (269)

Design and fabrication of conformal cooling channels in molds

open access: yesInternational Journal of Heat and Mass Transfer, 2021
Conformal cooling (CC) channels are a series of cooling channels that are equidistant from the mold cavity surfaces. CC systems show great promise to substitute conventional straight-drilled cooling systems as the former can provide more uniform and efficient cooling effects and thus improve the production quality and efficiency significantly. Although
Feng, Shaochuan   +2 more
openaire   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Designing Conformal Cooling Channels for Tooling

open access: yes, 1998
SFF technologies have demonstrated the potential to produce tooling with cooling channels which are conformal to the molding cavity. 3D Printed tools with conformal cooling channels have demonstrated simultaneous improvements in production rate and ...
Allen, Samuel   +3 more
core   +1 more source

Optimizing Laser Sintering Parameters and Cooling Channel Designs for Enhanced Injection Molding of Medical Tube Connectors

open access: yesJournal of Applied Science and Engineering
Respiratory equipment disconnections in hospitals pose severe risks, including hypoxia and mortality. Suboptimal tube connector quality, often worsened by traditional cooling mold designs, results in uneven thermal equilibrium, product deformation, and ...
Ding Yang Hsu
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Influence of Conformal Cooling Channel Parameters on Hot Stamping Tool and Press-Hardening Process

open access: yes, 2022
Press hardening is a technology increasingly used in the automotive industries to produce high-strength structural parts in boron steel. The part strengthening is due to a martensitic microstructure, which is obtained during the quenching phase of the ...
Maria Emanuela Palmieri, Luigi Tricarico
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Innovative Processing of Compacted Waste Aluminum Alloy Powders via Controlled Remelting and Solidification

open access: yesAdvanced Engineering Materials, EarlyView.
This study demonstrates an efficient recycling route for out‐of‐spec AlSi10Mg atomized powders through compaction and arc remelting followed by suction casting. By correlating compaction load, cooling rate, and resulting microstructure, we show that intermediate pressures (50–80 kN) and rapid cooling refine dendrites, reduce porosity, and enhance ...
Mila Christy de Oliveira   +4 more
wiley   +1 more source

Direct Metal Deposition of Graphene–Ti28Nb35.4Zr Matrix Composites With Enhanced Mechanical, Corrosion, and Biocompatibility Properties for Bone Implants

open access: yesAdvanced Engineering Materials, EarlyView.
Graphene nanoplatelet (0.1 wt.%) reinforcement significantly enhances the performance of β Ti‐28Nb‐35.4Zr alloy. Grain refinement, reduced water contact angle, and improved surface characteristics promote osteoblast adhesion and complete surface coverage after 7 days.
Khurram Munir   +5 more
wiley   +1 more source

Designing Polymer Nanocomposites for X‐Ray Shielding: Mechanisms, Architectures, and Scalable Processing

open access: yesAdvanced Engineering Materials, EarlyView.
This review highlights advances in lightweight, lead‐free polymer nanocomposites for diagnostic X‐ray shielding. By linking filler chemistry, dispersion, architecture, and photon interaction mechanisms, it establishes structure–performance relationships guiding material design.
Aklilu G. Messele   +2 more
wiley   +1 more source

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