Results 101 to 110 of about 4,829,113 (325)

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Virtual Mass of Any Shape of Body by using General Mapping Function

MATEC Web of Conferences, 2017
When an object is moving in acceleration with fluid interaction from surrounding, it possesses virtual mass (added mass) in which the total mass of object is higher than the original mass.
Arai Norio
doaj   +1 more source

Newark map 1915

, 1915
Map encompasses Newark, Harrison, Kearney, Irvington and East Newark. Ward numbers and boundries are shown in red.

core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Truk Islands: special strategic map.

, 1962
Scale 1:1,000,000 ; Lambert conformal conic projection, standard parallels 7° and 20°, (E 148°--E 154°/N 10°--6°). 1 map : color ; 46 x 68 cm. Edition 1-AMS. Compiled by the Army Map Service, February 1943.
United States. Army Map Service.
core   +1 more source

General f-harmonic morphisms

Arab Journal of Mathematical Sciences, 2016
In this paper, we prove that a map between Riemannian manifolds is an f-harmonic morphism in a general sense if and only if it is horizontally weakly conformal, satisfying some conditions, and we investigate the properties of f-harmonic morphism in a ...
Nour Elhouda Djaa, Ahmed Mohamed Cherif
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Feature-Driven Topology Optimization of Conformal Cooling Channel Structures Based on Parametric Mapping

Applied Sciences
Thin-walled conformal cooling structures are essential for the thermal management of complex curved electronic and aerospace devices. The traditional topology optimization of conformal cooling structures requires cumbersome post-processing reconstruction
Ying Zhou, Jingyi Xu, Linsheng He, Yang Tian, Yingang Liu, Jihong Zhu, Weihong Zhang   +6 more
doaj   +1 more source

Optimization Of Conformal Cartographic Projections For The Slovak Republic According To Chebyshev’s Theorem

Slovak Journal of Civil Engineering, 2015
Disadvantages of the currently used Křovák’s map projection in the Slovak Republic, such as large scale distortion, became evident after the division of Czechoslovakia.
Szatmári Daniel
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source