Results 71 to 80 of about 6,360 (266)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Journal of High Energy Physics, 2019 In the framework of six-dimensional conformal field theories with N = 1 , 0 $$ \mathcal{N}=\left(1,\ 0\right) $$ supersymmetry we develop the map between the holographic description, the field theoretical description and the associated Hanany-Witten set ...
Kostas Filippas +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Virtual Mass of Any Shape of Body by using General Mapping Function
MATEC Web of Conferences, 2017 When an object is moving in acceleration with fluid interaction from surrounding, it possesses virtual mass (added mass) in which the total mass of object is higher than the original mass.
Arai Norio
doaj +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Arab Journal of Mathematical Sciences, 2016 In this paper, we prove that a map between Riemannian manifolds is an f-harmonic morphism in a general sense if and only if it is horizontally weakly conformal, satisfying some conditions, and we investigate the properties of f-harmonic morphism in a ...
Nour Elhouda Djaa, Ahmed Mohamed Cherif
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Slovak Journal of Civil Engineering, 2015 Disadvantages of the currently used Křovák’s map projection in the Slovak Republic, such as large scale distortion, became evident after the division of Czechoslovakia.
Szatmári Daniel
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
The Fractional Carleson Measures on the Unit Ball of ℝn+1
Journal of Function Spaces and Applications, 2013 We construct a quantity in terms of Lp integral of the Jacobian of a conformal self-map on the unit ball of ℝn+1. Then, we characterize the fractional Carleson measures on the unit ball by the quantity.
Dongfang Wang, Bolin Ma
doaj +1 more source