Results 191 to 200 of about 97,061 (270)

Impact of extended insurance coverage on survival outcomes among patients with metastatic colorectal cancer in Taiwan

British Journal of Clinical Pharmacology, EarlyView.
Aims Predetermined treatment duration limits (PTDLs) are often used by Taiwan's National Health Insurance Administration to contain healthcare costs, but they may compromise patient outcomes. Therefore, we studied Taiwan's 2017 extension of the bevacizumab PTDL from 24 to 36 weeks in metastatic colorectal cancer (mCRC) to evaluate whether prolonged ...
Wei‐Ming Huang, Chen‐Han Chueh, Chien‐Yu Tseng, Christopher N. Kaufmann, Earl J. Morris, Chiao‐En Wu, Yi‐Wen Tsai   +6 more
wiley   +1 more source

The Respiratory Effects of Jet Fuel Exposure: A Fit-for-Purpose Systematic Literature Review and Evidence Synthesis. [PDF]

J Occup Environ Med
Bowers EC, Martin EM, Clemons M, Kolanowski A, Freedman AN, Starnes HM, Bergeron JG, Vidal J, Kotulkar M, Renda RP, Goodman SJ, Sprowles JLN, Falvo MJ, Snow SJ, Eftim SE, Haver CE, Vincent-Hall TD.   +16 more
europepmc   +1 more source

Nonadherence and uncontrolled arterial hypertension in Croatia—Insights from the May Measurement Month 2023 campaign and Hunting the silent killer programme

British Journal of Clinical Pharmacology, EarlyView.
Aims To determine the prevalence of non‐adherence to antihypertensive medicines and to identify demographic and behavioral factors associated with non‐adherence in subjects enrolled in the May Measurement Month (MMM) 2023, as part of the permanent public health action Hunting the silent killer.
Valerija Bralić Lang, Ana Soldo, Olgica Velkovski Škopić, Sunčana Vlah Tomičević, Tin Šaban, Andrej Belančić, Ana Jelaković, Josipa Josipović, Mihaela Marinović Glavić, Ivan Pećin, Luka Prgomet, Tajana Željković Vrkić, Bojan Jelaković   +12 more
wiley   +1 more source

Health Effects Associated With Jet Fuel Exposure: Methods for a Fit-for-Purpose Systematic Review and Systematic Evidence Map. [PDF]

J Occup Environ Med
Bergeron JG, Cameron RL, Goodman SJ, Sprowles JLN, Snow SJ, Eftim SE, Haver CE, Vincent-Hall TD.   +7 more
europepmc   +1 more source

Through the lens of marketing authorization holders: experience in use of real‐world data and real‐world evidence in drug development and regulatory submissions in EU

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola, Aleksandar Gigov, Hubertus G. M. Leufkens, Andrew Bate, Marie Louise De Bruin, Helga Gardarsdottir   +5 more
wiley   +1 more source

Response to the commentary on "Pre- and post-COVID-19 pandemic identification of dengue hotspots and exploration of determinants in Quezon City, Philippines". [PDF]

Trop Med Health
Medina JRC, Kawamura S, Takeuchi R, Cruz RV, Mendoza J, Hernandez PMR, Garcia FB, Gregorio ER, Kobayashi J.   +8 more
europepmc   +1 more source

Completion vs. early discontinuation of chemotherapy and the impact on 5‐year all‐cause mortality in women treated for early‐stage breast cancer from 2015 to 2020: A cohort study using a target trial emulation approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Chemotherapy is given for early‐stage breast cancer; however, some patients discontinue before completing all planned cycles. This study investigated the impact of early chemotherapy discontinuation on treatment outcomes. Methods This retrospective cohort study used a target trial emulation framework to conduct a causal analysis of the all‐
Luke Steventon, Chengsheng Ju, Kenneth K. C. Man, Rebecca Roylance, Diego Ottaviani, Chiara Creed, Michal Sladkowski, Alec Wisner, Li Wei, Pinkie Chambers   +9 more
wiley   +1 more source

Immune and environmental predictors of disease severity in atopic dermatitis: a retrospective cohort study. [PDF]

Am J Transl Res
Wu H, Wu Z, Shen Y, Zhang L, Yang M, Ren Y, Mao F.   +6 more
europepmc   +1 more source

Risk of injury associated with the sedative potential of second‐generation antihistamines: A nationwide retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Individual second‐generation antihistamines may possess differential sedative potential due to the variability in central histamine receptor H1 occupancy. This study aimed to evaluate whether the sedative potential of second‐generation antihistamines is associated with the risk of injury during Japan's pollen season. Methods We conducted a
Jumpei Taniguchi, Shotaro Aso, So Sato, Hideo Yasunaga   +3 more
wiley   +1 more source

Prospective cohort studies and their contribution to public health end evidence-based medicine. [PDF]

J Bras Pneumol
Zabert G, Patino CM, Ferreira JC.
europepmc   +1 more source