Results 51 to 60 of about 7,536,002 (274)

Controlling for continuous confounding factors: non- and semiparametric approaches.

, 2005
Confounding is one of the major types of bias encountered in observational epidemiologic surveys designed to study the relation between an exposure factor and a health event.
Werwatz, Axel, Slama, Rémy
core   +7 more sources

Short-term Effects of Carbon Monoxide on Mortality: An Analysis within the APHEA Project [PDF]

, 2007
Objectives: We investigated the short-term effects of carbon monoxide on total and cardiovascular mortality in 19 European cities participating in the APHEA-2 (Air Pollution and Health: A European Approach) project.
Vonk, J, Skorkovsky J, Skorkovsky, Jiri, Schwartz, J, Touloumi G, Mitja Košnik, Bertil Forsberg, Forsberg, Bertil,, Touloumi, G, Schindler, C, Maria Angela Vigotti, Touloumi, Giota, Vonk, Judith, Vonk J, Christian Schindler, Anderson, Hugh Ross, Evangelia Samoli, Košnik, Mitja, Klea Katsouyanni, Jiri Skorkovsky, Schindler C, Samoli, Evangelia, Forsberg, B, Hugh Ross Anderson, Forsberg, Bertil, Schwartz, Joel, Katsouyanni, Klea, Anderson, HR, Skorkovsky, J, Katsouyanni, K, Kosnik M, Vigotti, MA, Schwartz J, Katsouyanni K., Judith Vonk, Vigotti, Maria Angela, Joel Schwartz, Samoli, E, Kosnik, M, Forsberg B, Giota Touloumi, Schindler, Christian, Anderson HR, Samoli E   +43 more
core   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Accurate modeling of confounding variation in eQTL studies leads to a great increase in power to detect trans-regulatory effects [PDF]

, 2011
Expression quantitative trait loci (eQTL) studies are an integral tool to investigate the genetic component of gene expression variation. A major challenge in the analysis of such studies are hidden confounding factors, such as unobserved covariates or ...
Neil Lawrence, Oliver Stegle, Nicolo Fusi   +2 more
core  

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Potential misinterpretations caused by collapsing upper categories of comorbidity indices: An illustration from a cohort of older breast cancer survivors

Clinical Epidemiology, 2009
Thomas P Ahern1, Jaclyn LF Bosco2, Rebecca A Silliman2, Marianne Ulcickas Yood3, Terry S Field4, Feifei Wei5, Timothy L Lash1, On behalf of the BOW Investigators1Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA ...
Thomas P Ahern, Jaclyn LF Bosco, Rebecca A Silliman, Marianne Ulcickas Yood, et al.   +4 more
doaj  

Epidemiologic Design Bias, Confounders, And Interaction

, 2022
Epidemiologic investigations and research studies attempt to explore the occurrence of a health event or disease within a population. This chapter provides an understanding of the different types of research bias and describes the strategies to impact ...
Porche, Demetrius J.
core   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

A Review of Mendelian Randomization: Assumptions, Methods, and Application to Obesity-Related Diseases

Journal of Obesity & Metabolic Syndrome
Mendelian randomization (MR) is a statistical method that uses genetic variants as instrumental variables to estimate the causal effect of exposure on an outcome in the presence of unmeasured confounding.
Seungjae Lee, Woojoo Lee
doaj   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source