Results 111 to 120 of about 1,899,712 (390)

Integrated ‘Shield‐Spear’ Biological Patch for Fibrosis‐Free Bladder Reconstruction

Advanced Science, EarlyView.
Fibrosis‐free bladder reconstruction remains challenging. This study pioneers an integrated “shield‐spear” patch: The outer anionic hydrogel layer captures GATA6+ macrophages to suppress collagen overexpression, while the inner S100 aptamer‐engineered EVs target Schwann cells to downregulate the TGFβ/Smad pathway—inhibiting fibrosis with enhanced wound
Xiaoqi Wu, Huitong Ruan, Xiaolin Zhang, Weihan Zheng, Muhetaierjiang Mutailifu, Ling Wang, Liu Yu, Ruijun Peng, Rui Zhao, Zihan Wang, Jie Xu, Shaochuan Li, Yaobin Wu, Wenguo Cui, Mujun Lu   +14 more
wiley   +1 more source

Chest CT scoring for evaluation of lung sequelae in congenital diaphragmatic hernia survivors

, 2020
Objectives Data on long-term structural lung abnormalities in survivors of congenital diaphragmatic hernia (CDH) is scarce. The purpose of this study was to develop a chest computed tomography (CT) score to assess the structural lung sequelae in CDH ...
Aukland, Stein M., Beel, Emma, Boon, Mieke, Debeer, Anne, Proesmans, Marijke, Vermeulen, François   +5 more
core   +1 more source

Congenital disorders of glycosylation.

Annals of Translational Medicine, 2018
Congenital disorders of glycosylation are a genetically and clinically heterogeneous group of >130 diseases caused by defects in various steps along glycan modification pathways.
I. Chang, M. He, Christina Lam
semanticscholar   +1 more source

AGAPIR: A Novel PIWI‐Interacting RNA Enhancing Post‐Decompression Angiogenesis in Degenerative Cervical Myelopathy

Advanced Science, EarlyView.
The restoration of blood flow following surgical decompression for degenerative cervical myelopathy (DCM) significantly contributes to the amelioration of neurological deficits. This study identifies AGAPIR, an angiogenesis‐associated PIWI‐interacting RNA, enhances angiogenesis and motor function recovery post‐spinal cord decompression in a mouse model
Yongheng Xie, Yiling Peng, Tianyu Qin, Cuimei Chen, Zhenxiao Ren, Naibo Feng, Chungeng Liu, Songlin Peng, Houqing Long   +8 more
wiley   +1 more source

Coronavirus disease 2019 in patients with Fontan circulation

International Journal of Cardiology Congenital Heart Disease, 2021
Flavia Fusco, Giancarlo Scognamiglio, Assunta Merola, Michela Palma, Anna Correra, Nunzia Borrelli, Rosaria Barracano, Nicola Grimaldi, Diego Colonna, Emanuele Romeo, Berardo Sarubbi   +10 more
doaj   +1 more source

Incidence of symptomatic toxoplasma eye disease: aetiology and public health implications. [PDF]

, 1999
Ocular disease is the commonest disabling consequence of toxoplasma infection. Incidence and lifetime risk of ocular symptoms were determined by ascertaining affected patients in a population-based, active reporting study involving ophthalmologists ...
Dunn, DT, Gilbert, RE, Gormley, PD, Lightman, S, Masters, J, Murray, PI, Parker, SP, Pavesio, CE, Stanford, MR   +8 more
core   +2 more sources

Congenital Chagas disease: Updated recommendations for prevention, diagnosis, treatment, and follow-up of newborns and siblings, girls, women of childbearing age, and pregnant women

PLoS Neglected Tropical Diseases, 2019
In 2005, the World Health Organization (WHO) recognized Chagas disease (CD; Trypanosoma cruzi infection) as a neglected tropical disease (NTD) [1] and included it into the global plan to combat NTDs [2].
Y. Carlier, J. Altcheh, A. Angheben, H. Freilij, A. Luquetti, A. Schijman, M. Segovia, N. Wagner, Pedro Albajar Viñas   +8 more
semanticscholar   +1 more source

PCSK9 Loss‐of‐Function Disrupts Cellular Microfilament Network via LIN28A/HES5/JMY Axis in Neural Tube Defects

Advanced Science, EarlyView.
PCSK9 acts as a molecular chaperone promoting LIN28A lysosomal degradation. LIN28A elevates transcription factor HES5, increasing JMY expression. PCSK9 loss causes neural tube defects (NTDs) by disrupting the LIN28A/HES5/JMY axis, and high JMY disorganizes the neural progenitor cell microfilament network, leading to incomplete neural tube structure in ...
Xiaoshuai Li, Rui Wang, Wenting Luo, Hui Gu, Tianchu Huang, Qiushi Wang, Zhengwei Yuan   +6 more
wiley   +1 more source

Biomimetic Thermal Safety Strategies in Batteries for Electric Vehicles: from Biological Principles to Engineering Approaches

Advanced Science, EarlyView.
Biological principles derived from natural structures and functions inspire novel biomimetic strategies for battery thermal safety. This review summarizes applications of biomimetic concepts in preventing thermal runaway, highlighting design strategies that enhance thermal safety protection.
Weifeng Li, Zhongchun Wang, Yao Xue, Zhenhai Gao, Huanli Sun, Ximin Zhai, Deping Wang, Yupeng Chen   +7 more
wiley   +1 more source

Comparison of Early Outcomes for Normothermic and Hypothermic Cardiopulmonary Bypass in Children Undergoing Congenital Heart Surgery

Frontiers in Pediatrics, 2018
Objective: Comparison of early outcomes of normothermic cardiopulmonary bypass (N-CPB, ≥35°C) with hypothermic cardiopulmonary bypass (H-CPB, 28–34°C) for congenital heart defects.Methods: Data from 99 patients <2 years operated with N-CPB (n = 48) or
Antonio F. Corno, Antonio F. Corno, Claire Bostock, Simon D. Chiles, Joanna Wright, Maria-Teresa Jn Tala, Branko Mimic, Mirjana Cvetkovic   +7 more
doaj   +1 more source