Results 221 to 230 of about 968,479 (311)

Pharmacokinetics, Effectiveness and Safety of Certolizumab Pegol in Children and Adolescents With Active Juvenile Idiopathic Arthritis: 9+‐Year Results From a Multicenter, Open‐Label Study

Arthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to assess the pharmacokinetics, effectiveness, safety, and immunogenicity of certolizumab pegol (CZP) in polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods Pediatric Arthritis Study of Certolizumab Pegol (NCT01550003), a multicenter, open‐label study, enrolled patients aged 2 to 17 years with ...
Hermine I. Brunner, Lyudmila Grebenkina, Irina Nikishina, Ekaterina Alexeeva, Vyacheslav Chasnyk, Carlos Abud‐Mendoza, Nadina Rubio‐Pérez, Heinrike Schmeling, María del Rocio Maldonado‐Velázquez, Diane Brown, Andrew Zeft, Esi Morgan, C. Egla Rabinovich, Daniel Kingsbury, Hulya Bukulmez, Beth Gottlieb, Thomas Griffin, Lisa Imundo, Stacey Tarvin, Earl Silverman, Laura Shaughnessy, Saori Shimizu, Paulette Williams, Rocío Lledó‐García, Gauri Utturkar, Baran Ufuktepe, Alberto Martini, Daniel J. Lovell, Nicolino Ruperto, the Paediatric Rheumatology International Trials Organisation (PRINTO); the Pediatric Rheumatology Collaborative Study Group (PRCSG), Hermine I. Brunner, Lyudmila Grebenkina, Irina Nikishina, Ekaterina Alexeeva, Vyacheslav Chasnyk, Carlos Abud‐Mendoza, Nadina Rubio‐Pérez, Heinrike Schmeling, María del Rocio Maldonado‐Velázquez, Diane Brown, Andrew Zeft, Esi Morgan, C. Egla Rabinovich, Daniel Kingsbury, Hulya Bukulmez, Beth Gottlieb, Thomas Griffin, Lisa Imundo, Stacey Tarvin, Earl Silverman, Alberto Martini, Daniel L. Lovell, Nicolino Ruperto   +52 more
wiley   +1 more source

Congenital Clubfoot as an Early Manifestation of Duchenne Muscular Dystrophy? [PDF]

Muscles
Kenis V, Shpulev P, Melnik E, Sosnina I, Snegova E.   +4 more
europepmc   +1 more source

Initial treatment strategies and outcomes across haemodynamic thresholds and risk stratification in incident systemic sclerosis–associated pulmonary arterial hypertension: a EUSTAR analysis

Arthritis &Rheumatology, Accepted Article.
Objective Real‐world initial treatment strategies in SSc‐PAH remain incompletely described. We aimed to characterise these strategies across haemodynamic thresholds and risk strata and evaluate outcome associations. Methods We analysed treatment‐naïve SSc‐PAH patients in EUSTAR (2000–2021) fulfilling the 2022 haemodynamic definition.
Hilde Jenssen Bjørkekjær, Cosimo Bruni, Kaspar Broch, Cathrine Brunborg, Patricia E Carreira, Paolo Airò, Carmen Pilar Simeón‐Aznar, Marie‐Elise Truchetet, Alessandro Giollo, Alexandra Balbir‐Gurman, Mickael Martin, Christopher P Denton, Armando Gabrielli, Francesco Del Galdo, Madelon C. Vonk, Håvard Fretheim, Helle Bitter, Øyvind Midtvedt, Arne K. Andreassen, Sverre Høie, Yoshiya Tanaka, Gabriela Riemekasten, Ulf Müller‐Ladner, Marco Matucci‐Cerinic, Ivan Castellví, Elise Siegert, Eric Hachulla, Øyvind Molberg, Oliver Distler, Anna‐Maria Hoffmann‐Vold, on behalf of the EUSTAR collaborators   +30 more
wiley   +1 more source

Congenital Microgastria With Esophageal Stricture: An Extremely Rare Foregut Anomaly Necessitating Early Surgical Intervention. [PDF]

ACG Case Rep J
Gupta A, Aravind A, Srivastava A, Mandelia A, Sen Sarma M.   +4 more
europepmc   +1 more source

Evaluating discrepancies between high‐yield neuroscience conditions in preclerkship medical education and national clinical incidence

Anatomical Sciences Education, EarlyView.
Abstract Medical education must balance foundational science with clinical relevance. Increasing emphasis on standardized assessments has led to prioritization of “high‐yield” conditions—those most likely to be assessed. Subsequently, educators and students often prioritize these conditions.
Kathryn Veazey, Oheneba Boadum
wiley   +1 more source

Clinical characteristics and factors contributing to transmission of congenital syphilis in England, 2015-24: a national surveillance study. [PDF]

Lancet Reg Health Eur
Fifer H, Peters H, Kingston M, Francis K, Till R, Thorne C, Lyall H, Clinical Expert Review Panel.   +7 more
europepmc   +1 more source

Framing anatomical variation in anatomy textbooks: Language use and its implications

Anatomical Sciences Education, EarlyView.
Text mining of anatomy textbooks shows “abnormal” is the most frequently used descriptor for anatomical variation, reinforcing a binary framing. We advocate for explicit teaching of variation as a spectrum, with consistent, neutral terminology and contextualization (prevalence and functional relevance) to support a more nuanced understanding of ...
An‐Di Yim, Matthew Schell, Alexandra Zachwieja   +2 more
wiley   +1 more source

Use of Janus kinase inhibitors during early pregnancy in patients with rheumatic disease: a case series. [PDF]

EULAR Rheumatol Open
Needham A, Cheng V, Tan J, De Vera MA, Amiri N.   +4 more
europepmc   +1 more source

Arthroscopic Saucerization and Anatomic Repair of a Wrisberg Variant Discoid Lateral Meniscus: A Physeal‐Sparing Knotless Anchor Technique

Arthroscopy Techniques, EarlyView.
Abstract Discoid lateral meniscus (DLM) is a congenital variant of the knee characterized by an abnormally shaped meniscus prone to tearing and instability. When symptomatic, the treatment plan is based on the location and pattern of the tear, as well as the presence of instability.
Stephen Rossettie, Ann Hu, Dan Griffin, Greg Perraut, Ryan Murray   +4 more
wiley   +1 more source