Results 251 to 260 of about 350,440 (325)

Incidence and Type of Abnormal Karyotype in Foetuses with Major Congenital Malformations Detected on Prenatal Ultrasound

, 2018
Audimulapu Sujatha, Koorapati Suneetha
openalex   +1 more source

Impact of genotype–phenotype associations on prognosis in dilated cardiomyopathy

European Journal of Heart Failure, EarlyView.
Prediction of clinical outcomes in genetic dilated cardiomyopathy (DCM). LVEF, left ventricular ejection fraction. Aims Dilated cardiomyopathy (DCM) has a monogenic aetiology in up to 40% of patients. Understanding the spectrum of genotype–phenotype associations in DCM is crucial for risk stratification and personalized treatment.
Sophie L.V.M. Stroeks, Ping Wang, Marco Merlo, Steven Muller, Alessia Paldino, Nerea Mora‐Ayestaran, Max Jason, Matteo dal Ferro, Carola Pio Loco detto Gava, Fernando Dominguez, Esther Gonzalez‐Lopez, Arthur van den Wijngaard, Max F.G.H.M. Venner, Maurits Sikking, Michiel Minten, Bastien Nihant, Nina Beelen, Sharon Graw, Kristen Medo, Bart de Koning, Matthew Taylor, J. Peter van Tintelen, Luisa Mestroni, Gianfranco Sinagra, Anneline S.J.M. te Riele, Pablo Garcia‐Pavia, Stephane Heymans, Job A.J. Verdonschot   +27 more
wiley   +1 more source

Expanding congenital abnormalities of the kidney and urinary tract (CAKUT) genetics: basonuclin 2 (BNC2) and lower urinary tract obstruction. [PDF]

Ann Transl Med, 2019
Fernandez-Prado R, Kanbay M, Ortiz A, Perez-Gomez MV.   +3 more
europepmc   +1 more source

Deep phenotyping of heart failure with preserved ejection fraction through multi‐omics integration

European Journal of Heart Failure, EarlyView.
Deep phenotyping of of heart failure with preserved ejection fraction (HFpEF) through multi‐omics integration. AI, artificial intelligence. Aims Heart failure with preserved ejection fraction (HFpEF) has become the predominant form of heart failure and a leading cause of global cardiovascular morbidity and mortality.
Jakob Versnjak, Titus Kuehne, Pauline Fahjen, Nina Jovanovic, Ulrike Löber, Gabriele G. Schiattarella, Nicola Wilck, Holger Gerhardt, Dominik N. Müller, Frank Edelmann, Philipp Mertins, Roland Eils, Michael Gotthardt, Sofia K. Forslund, Benjamin Wild, Marcus Kelm   +15 more
wiley   +1 more source

Associations between the Level of Trace Elements and Minerals and Folate in Maternal Serum and Amniotic Fluid and Congenital Abnormalities. [PDF]

Nutrients, 2019
Kocylowski R, Grzesiak M, Gaj Z, Lorenc W, Bakinowska E, Barałkiewicz D, von Kaisenberg CS, Lamers Y, Suliburska J.   +8 more
europepmc   +1 more source

Congenital Abnormalities [PDF]

Nature, 1963
openaire   +1 more source

Effects of semaglutide in obesity‐related heart failure with preserved ejection fraction across the age spectrum: Findings from the STEP‐HFpEF programme

European Journal of Heart Failure, EarlyView.
Abstract Background The prevalence of heart failure with preserved ejection fraction (HFpEF) increases with age, and older adults with HFpEF have worse physical function, quality of life, and clinical outcomes. Semaglutide demonstrated efficacy in the treatment of obesity‐related HFpEF in the STEP‐HFpEF trials.
Ambarish Pandey, Michael Moroney, Subodh Verma, Barry A. Borlaug, Javed Butler, Melanie J. Davies, Dalane W. Kitzman, Sanjiv J. Shah, Mark C. Petrie, Cecilia Rönnbäck, Anne Domdey, Søren Rasmussen, Khaja M. Chinnakondepalli, Shachi Patel, Mikhail N. Kosiborod   +14 more
wiley   +1 more source

Zika Virus Infection during Pregnancy and Congenital Abnormalities. [PDF]

Front Microbiol, 2017
Rather IA, Lone JB, Bajpai VK, Park YH.
europepmc   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source