Results 301 to 310 of about 2,178,409 (393)

An open‐label, single‐arm, multicenter, phase II trial of bireociclib as monotherapy for heavily pretreated HR‐positive, HER2‐negative advanced breast cancer patients: BRIGHT‐1 trial

Cancer Communications, EarlyView.
Abstract Background Bireociclib (XZP‐3287) is a novel selective cyclin‐dependent kinase 4 and 6 (CDK4/6) inhibitor, with a favorable safety profile demonstrated in preclinical and phase I studies. BRIGHT‐1 aimed to further explore the efficacy and safety of bireociclib monotherapy in patients with locally advanced, recurrent or metastatic, hormone ...
Jiayu Wang, Qingyuan Zhang, Tao Sun, Huiping Li, Ying Cheng, Zhongsheng Tong, Huihui Li, Wei Li, Jingfen Wang, Yuee Teng, Xinhong Wu, Jing Cheng, Zhendong Chen, Zhengqiu Zhu, Li Wang, Mingming Liu, Xianghui Duan, Lingmei Xu, Binghe Xu   +18 more
wiley   +1 more source

Closure of a Late‐Onset Iatrogenic Left Ventricular Pseudoaneurysm Caused by Erosion of an Apical Muscular VSD Device

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT We report the case of a 3‐year‐old asymptomatic girl (12 kg, 96 cm) who was diagnosed with a large iatrogenic left ventricular pseudoaneurysm (LVP) on follow‐up ultrasound, 14 months after apical muscular ventricular septal defect (VSD) closure with a 10 mm Amplatzer Muscular VSD occluder (Abbott, USA) due to device erosion.
Raymond N. Haddad, Haytham Bou Houssein, Ahmed Adel Hassan, Mohamed Kasem   +3 more
wiley   +1 more source

Subtle spine abnormalities in patients with back pain: fracture vs. congenital anomaly. [PDF]

, 1978
D Resnick
openalex   +1 more source

Management of Cardiac Implantable Electronic Devices in Patients With Severe Symptomatic Tricuspid Regurgitation—Proposed Algorithm and Selected Case Examples

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Severe tricuspid regurgitation (TR) is associated with significant morbidity and mortality. Management of severe TR includes treatment of the underlying cause(s), medical therapy and less commonly surgical tricuspid valve repair. Newer transcatheter tricuspid valve repair devices show promise for those patients who remain symptomatic with ...
Mina M. Kerolos, Kevin Lee, David M. Najman, Mark D. Metzl, Mark J. Ricciardi   +4 more
wiley   +1 more source

An apparently higher molecular weight gamma-chain variant in a new congenital abnormal fibrinogen Tochigi characterized by the replacement of gamma arginine-275 by cysteine [PDF]

, 1988
N Yoshida, Keiko Ota, Masaaki Moroi, Michio Matsuda   +3 more
openalex   +1 more source

Novel Transthoracic Pulmonary Valve Implantation Using Self‐Expanding Salus Valve: A Prospective Study of Safety and Mid‐Term Outcomes

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Transcatheter pulmonary valve replacement (TPVR) has emerged as a valuable treatment for severe pulmonary regurgitation (PR). The Salus valve (Balance Medical Technology Co. Ltd., Beijing, China) represents a novel self‐expanding valve stent designed for deployment through a transthoracic approach with a small subxiphoid incision ...
Ziqin Zhou, Miao Tian, Jiazichao Tu, Yong Zhang, Jian Zhuang, Shusheng Wen, Jimei Chen   +6 more
wiley   +1 more source

Contemporary Perspectives on Chronic Renal Disorders

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok, Poornima Ajay Manjrekar, Bhushan C. Shetty, Sujina S. S, Rukmini Mysore Srikantiah, Sowndarya Kollampare   +5 more
wiley   +1 more source

Congenital abnormalities in calves associated with Peaton virus infection in Japan. [PDF]

J Vet Diagn Invest, 2018
Matsumori Y, Aizawa M, Sakai Y, Inoue D, Kodani M, Tsuha O, Beppu A, Hirashima Y, Kono R, Ohtani A, Yanase T, Shirafuji H, Kato T, Tanaka S, Yamakawa M.   +14 more
europepmc   +1 more source

A new congenital platelet abnormality characterized by spontaneous platelet aggregation, enhanced von Willebrand factor platelet interaction, and the presence of all von Willebrand factor multimers in plasma [PDF]

, 1989
Alessandra Casonato, Luigi De Marco, M. Mazzucato, Vincenzo De Angelis, Dina De Roia, F. Fabris, ZM Ruggeri, Antonio Girolami   +7 more
openalex   +1 more source

Congenital haemolytic anaemia associated with abnormal inducible red cell cation permeability. [PDF]

, 1983
R M Gardiner, N D Barnes, J. Clive Ellory   +2 more
openalex   +1 more source