Results 311 to 320 of about 2,178,409 (393)

The Heterotaxy Gene CCDC11 Is Important for Cytokinesis via RhoA Regulation

Cytoskeleton, EarlyView.
ABSTRACT Mutations in CCDC11 (cfap53) have been identified in multiple patients with heterotaxy (Htx), a disorder of left–right (LR) patterning of the internal organs. In Xenopus, depletion of Ccdc11 causes defects in LR patterning, recapitulating the patient phenotype. Upon Ccdc11 depletion, monociliated cells of the Left–Right Organizer (LRO) exhibit
Saurabh S. Kulkarni, Rachel E. Stephenson, Sarah Amalraj, Angelo Arrigo, Ewelina Betleja, James J. Moresco, John R. Yates III, Moe R. Mahjoub, Ann L. Miller, Mustafa K. Khokha   +9 more
wiley   +1 more source

Prenatal and Early Childhood Exposure to Antibiotics or Gastric Acid Inhibitors and Increased Risk of Epilepsy: A Nationwide Population‐Based Study

Clinical Pharmacology &Therapeutics, EarlyView.
Over 10 million children in the world have epilepsy, with an unknown cause in half of the cases. The gut microbiome has been associated with various neurological disorders, and certain drugs greatly disturb the microbiome. Our aim was to study the association of prenatal and childhood exposure (before the age of two) to antibiotics, proton pump ...
Unnur Gudnadottir, Ronny Wickström, Anna Gunnerbeck, Stefanie Prast‐Nielsen, Nele Brusselaers   +4 more
wiley   +1 more source

Pupillary Abnormalities in Congenital Neurosyphilis [PDF]

, 1985
M. Sundaram
openalex   +1 more source

Associations between the Level of Trace Elements and Minerals and Folate in Maternal Serum and Amniotic Fluid and Congenital Abnormalities. [PDF]

Nutrients, 2019
Kocylowski R, Grzesiak M, Gaj Z, Lorenc W, Bakinowska E, Barałkiewicz D, von Kaisenberg CS, Lamers Y, Suliburska J.   +8 more
europepmc   +1 more source

Knockout of rbm24a and rbm24b genes in zebrafish impairs skeletal and cardiac muscle integrity and function during development

Developmental Dynamics, EarlyView.
Abstract Backgound Skeletal and cardiac muscles are contractile tissues whose development and function are dependent on genetic programs that must be precisely orchestrated in time and space. In addition to transcription factors, RNA‐binding proteins tightly regulate gene expression by controlling the fate of RNA transcripts, thus specific proteins ...
Audrey Saquet, Ziwei Ying, De‐Li Shi, Raphaëlle Grifone   +3 more
wiley   +1 more source

Congenital Abnormalities of the Male Reproductive System and Risk of Autism Spectrum Disorders. [PDF]

Am J Epidemiol, 2018
Rotem RS, Chodick G, Davidovitch M, Hauser R, Coull BA, Weisskopf MG.   +5 more
europepmc   +1 more source

Congenital Abnormalities and Anticonvulsant Drugs

, 1970
S R Meadow
openalex   +1 more source

Congenital Abnormality of the Rectum [PDF]

Proceedings of the Royal Society of Medicine, 1933
openaire   +3 more sources

Trametinib alters contractility of paediatric Noonan syndrome‐associated hypertrophic myocardial tissue slices

ESC Heart Failure, EarlyView.
Abstract Aims No curative treatment is available for RASopathy‐associated childhood‐onset hypertrophic cardiomyopathy (RAS‐CM). Preclinical data and individual reports suggest a beneficial effect of small molecules targeting the RAS–mitogen‐activated protein (MAP) kinase (MAPK) pathway in severely affected RAS‐CM patients.
Jules Hamers, Payel Sen, Sarala Raj Murthi, Laura Papanakli, Maria von Stumm, Francesca Baessato, Julie Cleuziou, Christian Meierhofer, Peter Ewert, Andreas Dendorfer, Daphne Merkus, Cordula M. Wolf   +11 more
wiley   +1 more source

Prenatal ultrasound diagnosis of poland syndrome [PDF]

, 2004
D'ARMIENTO, MARIA, MARTINELLI, PASQUALE, PALADINI, DARIO   +2 more
core   +1 more source