Results 21 to 30 of about 2,109 (161)

A Pitx3-deficient developmental mouse model for fine motor, olfactory, and gastrointestinal symptoms of Parkinson's disease

Neurobiology of Disease, 2022
Parkinson's disease (PD) is characterized by the selective death of substantia nigra pars compacta (SNpc) dopaminergic neurons and includes both motor and non-motor symptoms.
Bin Song, Jacob W. Feldmann, Shibo Cao, Melissa Feitosa, Youngbin Kong, Woori Kim, Altana Schweitzer, Pierre Leblanc, Jeffrey S. Schweitzer, Kwang-Soo Kim   +9 more
doaj   +1 more source

Management of Aphakia with Visual Axis Opacification after Congenital Cataract Surgery Based on UBM Image Features Analysis

Journal of Ophthalmology, 2020
Objective. The purpose of this study was to study the imaging features of ultrasound biomicroscopy (UBM) in the aphakia with visual axis opacification (VAO) after congenital cataract surgery. Methods.
Wensi Chen, Shiping He, Daoman Xiang
doaj   +1 more source

Primary versus secondary intraocular lens implantation in the management of congenital cataract

Journal of the Egyptian Ophthalmological Society, 2016
Aim This study aimed to compare the efficacy of primary intraocular lens (IOL) implantation following removal of congenital cataract in patients with aphakia younger than 2 years of age, followed by secondary implantation after the age of 2 years ...
Thanaa H Mohamed, Rania G Eldin Zaki, Mohamed H Hashem   +2 more
doaj   +1 more source

The role of primary intraocular lens implantation in the risk of secondary glaucoma following congenital cataract surgery: A systematic review and meta-analysis.

PLoS ONE, 2019
OBJECTIVE:This meta-analysis aims to evaluate the incidence of secondary glaucoma in patients under the age of 2 years who underwent congenital cataract surgery with or without primary intraocular lens (IOL) implantation. METHODS:An electronic literature
Shuo Zhang, Jiaxing Wang, Ying Li, Ye Liu, Li He, Xiaobo Xia   +5 more
doaj   +1 more source

Incidence and management of rhegmatogenous retinal detachment after pars plana vitrectomy and sutureless scleral-fixated intraocular lens

Indian Journal of Ophthalmology, 2020
Purpose: To evaluate the incidence, risk factor(s), and surgical outcomes of rhegmatogenous retinal detachment (RRD) in patients undergoing pars plana vitrectomy (PPV) with sutureless scleral-fixated intraocular lens implantation (SFIOL).
Karthik Kumar, Piyush Kohli, Naresh Babu, Gauri Khare, Kim Ramasamy   +4 more
doaj   +1 more source

Transconjunctival XEN45 implantation for secondary open-angle glaucoma management in a pediatric patient with WAGR syndrome

American Journal of Ophthalmology Case Reports, 2023
Purpose: To report a case of XEN45 gel stent implantation in a pediatric patient with WAGR syndrome as a successful surgical intervention in the management of multifactorial secondary open-angle glaucoma.
Brooklyn Rawlyk, Mitchell D. Thatcher, Shehla Rubab, Maria Gabriela Campos-Baniak   +3 more
doaj   +1 more source

Gene Panel Analysis Reveals Overlapping Genetic Causes of Inherited Cataracts and Other Ocular Phenotypes in Bulgarian Patients

Molecular Genetics &Genomic Medicine, Volume 14, Issue 7, July 2026.
We have identified 4 pathogenic/likely pathogenic changes and 2 variants of uncertain significance, 3 of which were novel. The identification of disease‐causing variants in the CRYAA, MYH9, RP2, and CLNC1 genes allowed us to establish an accurate genetic diagnosis of inherited cataract and to describe overlapping clinical phenotypes.
Kristiyana Vitanova, Kunka Kamenarova, Nevyana Veleva‐Krasteva, Kalina Mihova, Yoanna Kaneva, Reni Tzveova, Martin Georgiev, Delyan Georgiev, Ivanka Dimova, Alexander Oscar, Radka Kaneva   +10 more
wiley   +1 more source

Lens-Induced Uveitis Triggered by Intravitreal Injection 40 Years after Primary Congenital Cataract Surgery with Aphakia

Case Reports in Ophthalmology, 2020
We report a case of a 42-year-old male with a history of bilateral congenital cataract surgery performed at 2 years of age. The patient was left with aphakia, secondary glaucoma, and a history of diabetic macular edema in the setting of diabetes mellitus
Sophia El Hamichi, Rafael J. Aguilar, Veronica Kon Graversen, Aaron S. Gold, Audina M. Berrocal, Timothy G. Murray   +5 more
doaj   +1 more source

Nance‐Horan Syndrome: Further Delineation of the Affected Male and the Female Carrier Phenotypes

American Journal of Medical Genetics Part A, Volume 200, Issue 3, Page 642-652, March 2026.
ABSTRACT Nance‐Horan syndrome (NHS; OMIM 302350) is a rare, X‐linked syndrome characterized by bilateral congenital cataracts leading to profound vision loss, specific dental anomalies including characteristic screwdriver blade‐shaped incisors, facial anomalies, and intellectual disability.
Maria K. Haanpää, Chad R. Haldeman‐Englert, Marja Hietala, Melisa S. Tanverdi, Patrick P. Koty, Diana Brightman, Eniolami Dosunmu, Shailja Tibrewal, Savleen Kaur, Anupriya Kaur, Raj Kumar Verma, Alejandra G. de Alba Campomanes, Virginia Utz, Anne M. Slavotinek, Cynthia Curry   +14 more
wiley   +1 more source

The Outcome after Surgery of Patients with Congenital Cataract in the Outpatient Clinic of RSUD Dr. Soetomo Surabaya in January 2014 – January 2017

Juxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga, 2019
Introduction: Congenital cataract is a leading cause of childhood blindness. Congenital cataract is characterized by an opacification of the lens that has existed from birth or shortly after birth.
Lady Sherly Nuramalia, Indri Wahyuni, Prastiya Indra Gunawan   +2 more
doaj   +1 more source