Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam +4 more
wiley +1 more source
Tooth Germ Changes in Congenital Syphilis
A histopathological study was made on two cases of congenital syphilis, with special emphasis on the changes of developing tooth germ and surrounding jaw bones. Both cases were conlirmed to be syphilis by serology and tissue Levaditi staining method.
이석근, 임창윤, 지제근
core
Large population-based assessment of SARS-CoV-2 teratogenicity by profiling congenital anomalies during COVID-19 pandemic. [PDF]
Jehangir S +8 more
europepmc +1 more source
IRF‐1 modulates hepatic ferroptosis and aggravates liver ischemia/reperfusion injury via DYRK1α
IRF‐1 modulates hepatic ferroptosis and aggravates liver ischemia/reperfusion injury via DYRK1α. Abstract Background The purpose is to define the contribution of the interferon regulatory factor‐1–dual‐specificity tyrosine phosphorylation‐regulated kinase 1α (IRF‐1–DYRK1α) axis to hepatocellular ferroptosis during liver ischemia/reperfusion injury ...
Jinping Zhang +6 more
wiley +1 more source
Analysis and comparison of the trends in burden of congenital musculoskeletal and limb anomalies in China and worldwide from 1990 to 2021. [PDF]
Zou MC, Liu WD, Wang XD, Su GH, Liu Y.
europepmc +1 more source
In this study, we primarily simulated pathological myocardial remodeling induced by transverse aortic constriction surgery and found significant cardiac hypertrophy and fibrosis, characterized by deteriorated cardiac function. Oxidative stress response is considered as a pivotal pathological process, which contributes to inflammation and apoptosis of ...
Yijia Wang +12 more
wiley +1 more source
ABSTRACT The presence of antibiotics in water not only causes environmental pollution but also increases the growth of antibiotic‐resistant bacterial genes, which pose serious threats to human beings and other water residents. Large numbers of people are reportedly affected by the resistant bacterial genes, as many broad‐spectrum antibiotics are not ...
Amir Zada, Shohreh Azizi
wiley +1 more source
Atypical Change Detection in Sound Sequences: A Behavioral and Magnetoencephalography Study in Congenital Amusia. [PDF]
Lévêque Y +8 more
europepmc +1 more source
Abstract Domesticated European rabbits (Oryctolagus cuniculus) have long been chosen as laboratory model organisms. Despite this, there has been no definitive study of the vertebral musculature of wild rabbits. Relevant descriptions of well‐studied veterinary model mammals (such as dogs) are generally applicable, but not appropriate for a species ...
Nuttakorn Taewcharoen +3 more
wiley +1 more source
Placental Vascular Pathology Associated with Congenital Lymphocytic Choriomeningitis Virus Infection, Philadelphia, Pennsylvania, USA. [PDF]
Abraham A +3 more
europepmc +1 more source

