Results 211 to 220 of about 343,621 (301)

Characteristics and temporal trends of EU teratological safety signals and information dissemination to healthcare professionals in the Netherlands—A contribution of the ConcePTION project

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Although regulatory responses to safety signals have been studied, pregnancy‐specific data and their dissemination to medical professionals remain unclear. This study examined the characteristics and temporal trends of teratological safety signals prompting the European Medicines Agency to implement risk minimization measures.
Yrea R. J. van Rijt‐Weetink   +9 more
wiley   +1 more source

Pregnancy‐related effect on elexacaftor, tezacaftor and ivacaftor pharmacokinetics in women with cystic fibrosis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim The number of pregnancies among women with cystic fibrosis (wwCF) has steadily increased over the past decade. However, the pharmacokinetics (PK) of elexacaftor–tezacaftor–ivacaftor (ETI) during gestation remains uncharacterized, despite its widespread use in this population.
Paulette Magnas   +16 more
wiley   +1 more source

Patent Foramen Ovale-Induced Hypoxemia Unmasked During Pregnancy. [PDF]

open access: yesJACC Case Rep
Regev A   +9 more
europepmc   +1 more source

Animal empathy reconsidered: a multidimensional profile account

open access: yesBiological Reviews, EarlyView.
ABSTRACT Empathy is the glue that holds societies together and yet several fundamental questions about empathy persist. What is empathy (the definitional question)? Is it uniquely human and, if not, which nonhuman animals possess empathy (the distribution question)? Which type or quality of empathy is realized in different species (the quality question)
Albert Newen   +5 more
wiley   +1 more source

Pathophysiologic Consequences of Early Coarctation Stenting in a Longitudinal Porcine Model

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Novel stent technologies offer early intravascular treatment options for coarctation (COA). Mid‐to‐long‐term cardiovascular responses to early COA stent interventions are undefined. Aims We studied a porcine model of COA, with and without early stent implantation with serial dilation to adult aortic diameters, aiming to define ...
Leah M. Gober   +7 more
wiley   +1 more source

One Anatomy, Multiple Valve Choices: Interobserver Agreement in Selecting Transcatheter Pulmonary Valve

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
Methodological framework among international observers to understand clinical decision‐making and interobserver agreement in TPVR planning. ABSTRACT Background Transcatheter pulmonary valve replacement (TPVR) requires selecting the optimal device type, size, and position. Variability in anatomical shape may affect procedural planning.
Camilo E. Pérez‐Cualtán   +10 more
wiley   +1 more source

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