Hemophagocytic lymphohistiocytosis and congenital factor VII deficiency: a case report [PDF]
BMC Medical Genetics, 2018 Background Hemophagocytic lymfohistiocytosis (HLH) is a rare, life-threatening hyperinflammation, characterized by immune system over-activation resulting in hemophagocytosis. HLH could appear as a primary disease caused by mutations of immune-regulatory
Xiong Wang +4 more
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A 5-year-old Chinese boy with mild symptoms despite severe congenital factor VII deficiency: A case report [PDF]
Journal of International Medical ResearchCongenital factor VII deficiency is a rare autosomal recessive bleeding disorder characterized by markedly heterogeneous clinical phenotypes and reduced plasma factor VII activity.
Wei Luo +3 more
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Congenital factor VII deficiency as a cause of postpartum hemorrhage: A case report [PDF]
Case Reports in Women's HealthObstetric hemorrhage is one of the leading causes of maternal morbidity and mortality worldwide. However, coagulation disorders as an etiology are rare, with a prevalence of less than 1 %.
Janine Russeth Hernández Zanata +5 more
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Perioperative management in a patient with congenital factor VII deficiency following mechanical valve replacement: a case report [PDF]
Thrombosis JournalBackground Congenital factor VII deficiency (CFVIID) is a rare hemorrhagic disorder which elevates perioperative bleeding risks. Mechanical prosthesis mandates lifelong anticoagulation, while international normalized ratio (INR) of CFVIID deviates ...
Xiaokang Luo +3 more
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Psychosocial Impact and Disease Management in Patients with Congenital Factor VII Deficiency [PDF]
Journal of Blood Medicine, 2020 Skye Peltier,1 Angela Kellum,2 Janet Brewer,3 Alexander Duncan,4 David L Cooper,5 Hossam Saad5 1Center for Bleeding and Clotting Disorders, University of Minnesota Medical Center - Fairview, Minneapolis, MN, USA; 2Louisiana Center for Bleeding and ...
Peltier S +5 more
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Treatment of Deep Vein Thrombosis in Congenital Factor VII Deficiency: A Case Report and Literature Review [PDF]
Clinical Case ReportsManaging thrombosis in patients with bleeding disorders requires careful assessment of thromboembolic and bleeding risks, tailoring antithrombotic treatment in terms of type, dose, and duration, and considering the need for replacement therapy based on ...
Synnøve Gjelsten Mortensen +4 more
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Continuous infusion of recombinant activated factor VII: a review of data in congenital hemophilia with inhibitors and congenital factor VII deficiency [PDF]
Journal of Blood Medicine, 2018 Madhvi Rajpurkar,1 David L Cooper2 1Division of Hematology/Oncology, Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Children’s Hospital of Michigan, Detroit, MI, USA; 2Clinical, Medical and Regulatory ...
Rajpurkar M, Cooper DL
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Expanded carrier screening and preimplantation genetic diagnosis in a couple who delivered a baby affected with congenital factor VII deficiency [PDF]
BMC Medical Genetics, 2018 Background Preimplantation genetic diagnosis (PGD) is a powerful tool for preventing the transmission of Mendelian disorders from generation to generation. However, PGD only can identify monogenically inherited diseases, but not other potential monogenic
Wen-Bin He +9 more
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A Phenotype-driven strategy for bilateral VATS in severe factor VII deficiency: securing hemostasis without complete parameter correction [PDF]
Journal of Cardiothoracic SurgeryBackground Perioperative management for severe Factor VII (FVII) deficiency in thoracic surgery typically aims to reduce bleeding risk by correcting coagulation parameters with factor replacement—a strategy limited by cost, thrombotic risk, and ...
Yun-Peng Yao +5 more
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Reply: factor II/X-guided warfarin monitoring for congenital factor VII deficiency after mechanical valve replacement [PDF]
Thrombosis JournalXiaokang Luo, Xinjian Yan
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