Results 81 to 90 of about 257,105 (351)

Metabolic alterations in human pulmonary artery smooth muscle cells treated with PDGF‐BB

Animal Models and Experimental Medicine, EarlyView.
Metabolic abnormalities are considered to play a key regulatory role in vascular remodeling of pulmonary arterial hypertension. We analyzed the metabolome in the culture supernatants of human pulmonary artery smooth muscle cells (PASMC) during the malignant proliferation phenotype transition via a targeted metabolomics method. Significant and extensive
Meng‐Jie Zhang, Jie‐Jian Kou, Hong‐Da Zhang, Xin‐Mei Xie, Yun‐Feng Zhou, Ping Yuan, Xiao‐Bin Pang, Lu‐Ling Zhao, Jing Qiu, Yang‐Yang He   +9 more
wiley   +1 more source

Early Neonatal and Postnatal Diagnostics, Clinical Manifestations, Treatment and Prognosis by Atrial Septal Defect

Zdorovʹe Rebenka, 2016
The article presents the published data on the pre­valence, the main clinical manifestations, modern methods of early neonatal and postnatal diagnosis, treatment and prognosis by atrial septal defect — the congenital malformation of cardiovascular system.
K.A. Kalashnikova, N.O. Nikitina
doaj   +1 more source

Exposure to pseudoephedrine during pregnancy and major congenital malformations: Findings from a large population‐based cohort of pregnancies

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of this study was to assess the risk of major congenital malformations following first‐trimester pseudoephedrine (PSE) exposure. Methods A population‐based observational cohort study was conducted on pregnancies of women aged 15–49 years, insured by Clalit Health Services in southern Israel, who gave birth or had elective ...
Saar Dor, Tal Michael, Yael Levi, Gali Pariente, Eitan Lunenfeld, Amalia Levy, Shira Birenstock‐Cohen, Sharon Daniel   +7 more
wiley   +1 more source

Common arterial trunk: pathomorphological changes of unoperated cardiac defect in adulthood

Patologìâ, 2018
Congenital heart defects in adulthood constitute the sufficient proportion of cardiac pathology. The common arterial trunk (CAT) is one of the сongenital cardiac defects that is described in the adult population.
V. I. Hryhoriichuk, Yu. I. Kuzyk, O. I. Boiko   +2 more
doaj   +1 more source

The tacrolimus concentration‐to‐dose ratio is associated with kidney function in heart transplant recipients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Heart transplantation (HT) is frequently complicated by chronic kidney disease, of which tacrolimus‐related nephrotoxicity is an important cause. In kidney and liver transplant recipients, fast tacrolimus metabolism (defined as a low concentration‐to‐dose [C0/D] ratio), negatively affects kidney function.
Maaike R. Schagen, Teun B. Petersen, Boris C. A. Seijkens, Jasper J. Brugts, Kadir Caliskan, Alina A. Constantinescu, Brenda C. M. de Winter, Isabella Kardys, Dennis A. Hesselink, Olivier Manintveld   +9 more
wiley   +1 more source

Closure of a Late‐Onset Iatrogenic Left Ventricular Pseudoaneurysm Caused by Erosion of an Apical Muscular VSD Device

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT We report the case of a 3‐year‐old asymptomatic girl (12 kg, 96 cm) who was diagnosed with a large iatrogenic left ventricular pseudoaneurysm (LVP) on follow‐up ultrasound, 14 months after apical muscular ventricular septal defect (VSD) closure with a 10 mm Amplatzer Muscular VSD occluder (Abbott, USA) due to device erosion.
Raymond N. Haddad, Haytham Bou Houssein, Ahmed Adel Hassan, Mohamed Kasem   +3 more
wiley   +1 more source

DOUBLE ANEUPLOIDY 48,XXY,+21 ASSOCIATED WITH A CONGENITAL HEART DEFECT IN A NEONATE

Balkan Journal of Medical Genetics, 2013
A neonate with a double aneuploidy associated with congenital heart defect (CHD) suffered from cyanosis after birth. He had typical features of Down syndrome (DS) including hypertelorism, slightly lowset ears with protruding pinna.
Shu X., Zou C., Shen Z.
doaj   +1 more source

Mycoplasma hominis endocarditis in a child with a complex congenital heart defect.

The Pediatric Infectious Disease Journal, 2006
We report a case of a 4-year-old girl with a complex congenital heart defect who developed Mycoplasma endocarditis after surgical repair. This is the first reported case of Mycoplasma endocarditis in a child and suggests consideration of this organism as
S. Dominguez, Cyndi Littlehorn, A. Nyquist   +2 more
semanticscholar   +1 more source

Emergent Cardiac Surgery After Transcatheter Structural Heart Procedures: Narrative Review

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Transcatheter structural heart procedures have become standard therapy for elderly patients with high surgical risk. Over time, these procedures have significantly increased worldwide, accompanied by a concomitant reduction of major complications, including those requiring emergent cardiac surgery (ECS).
Miriam Compagnone, Gianni Dall'Ara, Simone Grotti, Daniela Spartà, Giuseppe Guerrieri, Carmine Pizzi, Fabio Felice Tarantino, Marcello Galvani   +7 more
wiley   +1 more source

Frequency and pattern of adult congenital heart disease in a tertiary care cardiac hospital: reasons associated with delayed diagnosis

Journal of the Pakistan Medical Association
Objective: To determine the distribution pattern and possible reasons of delayed diagnosis of congenital heart disease in adult population. Method: The analytical, cross-sectional study was conducted at the Department of Paediatric Cardiology ...
Aliya Kemal Ahsan, Rumana Sangi, Abdul Sattar Shaikh, Mohammad Mohsin, Saba Mumtaz   +4 more
doaj   +1 more source