Results 121 to 130 of about 99,772 (304)

Trametinib alters contractility of paediatric Noonan syndrome‐associated hypertrophic myocardial tissue slices

ESC Heart Failure
Aims No curative treatment is available for RASopathy‐associated childhood‐onset hypertrophic cardiomyopathy (RAS‐CM). Preclinical data and individual reports suggest a beneficial effect of small molecules targeting the RAS–mitogen‐activated protein (MAP)
Jules Hamers, Payel Sen, Sarala Raj Murthi, Laura Papanakli, Maria vonStumm, Francesca Baessato, Julie Cleuziou, Christian Meierhofer, Peter Ewert, Andreas Dendorfer, Daphne Merkus, Cordula M. Wolf   +11 more
doaj   +1 more source

Mono‐dimensional, two‐dimensional and Doppler echocardiographic measurements in healthy Standardbred neonatal foals in the first 5 days of life

Equine Veterinary Journal, EarlyView.
Abstract Background Bodyweight, age and breed influence the echocardiographic assessment of foals. There are no echocardiographic studies in Standardbred neonatal foals. Objectives To describe echocardiographic values for selected variables, evaluate intra‐ and inter‐observer variability and assess cardiac changes in the first 5 days of life in healthy
Fernanda Timbó D'el Rey Dantas, Giulia Forni, Gayle Hallowell, Carolina Castagnetti, Laura Menchetti, Giovanni Romito, Aliai Lanci, Jole Mariella, Francesca Freccero   +8 more
wiley   +1 more source

Congenital Heart Defects in Children

To analyze the frequency and prevalence of congenital heart defects in a tertiary care center for children with heart diseases. METHODS: We carried out an epidemiological assessment of the first medical visit of 4,538 children in a pediatric hospital ...
Madhivanan, K. S. (Krishnasamy), Jayaasrii, T. S. (Thangavel), Aidanek, A. K. (Aidarbek), Sivakumar, P. (Periyasamy)   +3 more
core  

Roux‐en‐Y gastrojejunostomy and jejunojejunostomy for pyloric obstruction bypass in a horse and a foal

Equine Veterinary Journal, EarlyView.
Abstract Background Gastric outflow obstruction in horses is a rare but challenging condition, often resulting from either congenital anomalies or acquired lesions such as chronic ulceration or pyloric polyps. Conventional surgical bypass procedures, including gastrojejunostomy (GJ) or gastroduodenostomy and less commonly duodenojejunostomy, can ...
Marco Gandini, Nico Bolz, Christian Czech, Myria Hartman, Gessica Giusto   +4 more
wiley   +1 more source

Congenital heart defects: from a prenatal perspective

This thesis discusses the prenatal detection and outcome of fetal congenital heart defects. The first part of this thesis focuses to identify determinants for a prenatal diagnosis in fetus with a structural congenital heart defect.
Nisselrooij, A.E.L. van
core   +1 more source

Contribution of hypoxia-inducible factor 1alpha to pathogenesis of sarcomeric hypertrophic cardiomyopathy

Scientific Reports
Hypertrophic cardiomyopathy (HCM) caused by autosomal-dominant mutations in genes coding for structural sarcomeric proteins, is the most common inherited heart disease.
Sarala Raj Murthi, Andreas Petry, Bachuki Shashikadze, Jan B. Stöckl, Manuel Schmid, Gianluca Santamaria, Karin Klingel, Damir Kračun, Xinpei Chen, Sabine Bauer, Joachim P. Schmitt, Florian Flenkenthaler, Josh Gorham, Christopher N. Toepfer, David Potěšil, Pavel Hruška, Zbyněk Zdráhal, Zsuzsanna Mayer, Mathieu Klop, Luisa Lehmann, Yishi Qin, Laura Papanakli, Nadine Spielmann, Alessandra Moretti, Thomas Fröhlich, Peter Ewert, Stefan Holdenrieder, Jonathan G. Seidman, Christine E. Seidman, Agnes Görlach, Cordula M. Wolf   +30 more
doaj   +1 more source

Anatomical Variation of Absent Facial Vein: Implications for Facial Reanimation Surgery

Head &Neck, EarlyView.
ABSTRACT Background The facial vein is the standard recipient vessel in facial reanimation surgery. Its complete absence is rarely described but may cause major challenges during free functional muscle transfer (FFMT). This study aimed to determine the prevalence and predictors of facial vein absence and assess its surgical relevance in facial ...
Cam T. Nguyen, Mark Fricke, Justus Osterloh, Ayla A. Hohenstein, Steffen U. Eisenhardt   +4 more
wiley   +1 more source

The relationship between congenital heart defects and e-nos gene in down syndrome [PDF]

, 2016
WOS: 000395220700001PubMed ID: 30204958The relationship between congenital heart defects and e-NOS gene in Down syndrome: The aim of the study was to compare the effects of three eNOS gene polymorphisms associated with congenital heart defects, between ...
Okur, Mesut, Bektaş, Mehmet Selçuk, Türker, Yasin, Bahadır, Anzel, Eröz, Recep, Türker, Y., Güneş, Cemalettin, Gülşen, Süleyman   +7 more
core  

Juxtaposition of the atrial appendages in a patient with a simple ventricular septal defectCentral Message

JTCVS Techniques, 2021
Julie Cleuziou, MD, PhD, MBA, Jakob Kemmer, MD, Ursula Sauer, MD, Milka Pringsheim, MD   +3 more
doaj   +1 more source

Evaluation of a novel fetal echocardiography training programme in two tertiary care obstetric Centres

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objectives Improving and maintaining high detection rates for major congenital heart disease (CHD) is a priority for successful prenatal anatomy screening programmes. The primary objective of this study was to evaluate the utility of on‐site multidimensional targeted training in fetal cardiac screening. Methods A prospective study evaluating a
Fiona Cody, Orla Franklin, Caoimhe Lynch, Zara Molphy, Patrick Dicker, Fergal Malone, Fionnuala M. Breathnach   +6 more
wiley   +1 more source