Results 291 to 300 of about 355,187 (399)

Efficacy and Safety of the Topical Gene Therapy Beremagene Geperpavec‐svdt (B‐VEC) in an Open‐Label Study of Japanese Subjects With Dystrophic Epidermolysis Bullosa

The Journal of Dermatology, EarlyView.
ABSTRACT Dystrophic epidermolysis bullosa (DEB) patients have pathogenic variants in COL7A1, leading to skin fragility, blistering, and scarring. Beremagene geperpavec‐svdt (B‐VEC) is a replication‐defective herpes simplex virus type 1 (HSV‐1)‐based gene therapy vector administered topically to deliver functional COL7A1 to DEB wounds.
Ken Natsuga, Daisuke Tsuruta, Shota Takashima, Chiharu Tateishi, Masaaki Takatoku, Brittani Agostini, Sarrah Mailliard, Nicholas J. Reitze, Rebecca T. Beacham, Alexia M. Cardiges, Michael J. Johnston, Ramakrishna Edukulla, Suma M. Krishnan   +12 more
wiley   +1 more source

Cardiological rehabilitation, prehabilitation, and cardiovascular prevention in adults with congenital heart defects: tasks and services of the German Pension Insurance-part 1: preventive cardiology and prehabilitation. [PDF]

Cardiovasc Diagn Ther
Barth J, Dewald O, Ewert P, Freiberger A, Freilinger S, Gampert T, Harig F, Hörer J, Holdenrieder S, Huntgeburth M, Kaemmerer-Suleiman AS, Kohls N, Nagdyman N, Neidenbach R, Schmiedeberg W, Suleiman MN, von Scheidt F, Koch D, Wagener W, Mentzner D, Kaemmerer H, Mellert F.   +21 more
europepmc   +1 more source

Environmental causes of human congenital malformations: The physician\u27s role in dealing with these complex clinical problems caused by environmental and genetic factors. [PDF]

, 2008
Brent, Robert L
core   +1 more source

Years of Potential Life Lost for Children and Adults With Congenital Heart Defects: United States, 2007 to 2017. [PDF]

J Am Heart Assoc
Nembhard WN, Maity S, Bircan E, Politis MD, Bolin EH, Ying J.   +5 more
europepmc   +1 more source

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

Andrology, EarlyView.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

An individualised mobile app was beneficial for the mothers of infants with severe congenital heart defects. [PDF]

Acta Paediatr
Hjorth-Johansen E, Børøsund E, Moen A, Østen IM, Wik G, Solevåg AL, Eger SHW, Holmstrøm H.   +7 more
europepmc   +1 more source

Epidemiology of hypospadias in China: A nationwide surveillance‐based study, 2010–2020

Andrology, EarlyView.
Abstract Background The prevalence of hypospadias varied internationally. However, epidemiological data on hypospadias in contemporary China remain limited. Objectives We aim to examine the epidemiological characteristics of hypospadias in Chinese population.
Chen Zhiyu, Gao Yuyang, Xu Wenli, Li Wenyan, Liu Zhen, Zhou Jiayuan, Zhu Jun, Dai Li   +7 more
wiley   +1 more source

Amniotic fluid microbiota and metabolism with non-syndromic congenital heart defects: a multi-omics analysis. [PDF]

BMC Pregnancy Childbirth
Xu W, Li L, Kang H, Wang M, Liu Y, Wang G, Yu P, Liang J, Liu Z.   +8 more
europepmc   +1 more source

Difference in pre‐ and postnatal prevalence of congenital cardiac tumors in a large population‐based cohort

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Ultrasonic assessment of a large, contemporary cohort in Copenhagen, Denmark, revealed a prevalence of congenital cardiac tumors of 0.002% prenatally (gestational Weeks 18–21) and 0.027% postnatally. All cardiac tumors were located in the ventricles.
Anne‐Sophie Sillesen, Finn Stener Jørgensen, Olav Bjørn Petersen, Helle Zingenberg, Sofie Dannesbo, Anna Axelsson Raja, Ruth Ottilia Birgitta Vøgg, Niels Vejlstrup, Kasper Iversen, Henning Bundgaard   +9 more
wiley   +1 more source