Results 111 to 120 of about 429,935 (362)

Targeted Medical Therapies for Vascular Anomalies: A Clinical Review

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Vascular anomalies represent a broad spectrum of disorders characterized by aberrant blood or lymphatic vessel development, which can lead to complex clinical phenotypes. Historically, vascular anomalies were classified solely on the basis of their clinical and histopathologic features.
Whitney Eng
wiley   +1 more source

Prognostic value of right ventricular dyssynchrony in adults with repaired tetralogy of Fallot

Open Heart
Objective Residual sequelae after surgical repair of tetralogy of Fallot (rTOF) affect clinical outcome. We investigated the prognostic impact of right ventricular (RV) dyssynchrony in adults with rTOF years after the surgical repair.Methods Patients ...
Markus Schwerzmann, Matthias Greutmann, Daniel Tobler, Kerstin Wustmann, Andrea Papa, Clement Nussbaumer, Eleni Goulouti, Fabienne Schwitz   +7 more
doaj   +1 more source

Brain volumes predict neurodevelopment in adolescents after surgery for congenital heart disease [PDF]

, 2017
Patients with complex congenital heart disease are at risk for neurodevelopmental impairments. Evidence suggests that brain maturation can be delayed and pre- and postoperative brain injury may occur, and there is limited information on the long-term ...
Buchmann, Andreas, Hagmann, Cornelia, Huber, Reto, Klaver, Peter, Knirsch, Walter, Latal, Beatrice, von Rhein, Michael   +6 more
core  

Sleep Patterns in Young Children with Congenital Heart Disease

, 2022
Anjali Sadhwani, Samantha Butler, Valerie Rofeberg, Kristina Espinosa, Laura D. Wood, Adam R. Cassidy, Johanna Calderon, Caitlin K. Rollins, Jayne Singer, Brandi Henson, Catherine Ullman-Shade, Catherine D. Clark, David Wypij, Jane W. Newburger, David C. Bellinger, Janice Ware   +15 more
openalex   +2 more sources

Co‐Opting MBNL‐Dependent Alternative Splicing Cassette Exons to Control Gene Therapy in Myotonic Dystrophy

Annals of Neurology, EarlyView.
Objective Myotonic dystrophy type 1 (DM1) is a highly variable, multisystemic genetic disorder caused by a CTG repeat expansion in the 3′ untranslated region of DMPK. Toxicity is exerted by repeat‐containing DMPK transcripts that sequester muscleblind‐like (MBNL) proteins and lead to deleterious yet predictable changes in alternative splicing.
Samuel T. Carrell, Ellie M. Carrell, Ryan Giovenco, Beverly L. Davidson   +3 more
wiley   +1 more source

Feasibility and effectiveness of telemedicine for adult patients with congenital heart disease: A one-year single-center experience-based studySummary table

International Journal of Cardiology Congenital Heart Disease
Introduction: The number of adults with congenital heart disease has significantly increased in recent years. While telemedicine has emerged as a promising approach to improve care delivery and patient outcomes, its use for adults with congenital ...
Nunzia Borrelli, Nicola Grimaldi, Flavia Fusco, Antonio Orlando, Michela Palma, Maria Cristina Boccia, Sabrina Bassolino, Anna Iervolino, Berardo Sarubbi   +8 more
doaj   +1 more source

Clinical Importance of Concomitant Cleft Lip/Palate in the Surgical Management of Patients With Congenital Heart Disease

, 2021
Omar Toubat, Demetrios N. Mallios, Naikhoba C.O. Munabi, William P. Magee, Vaughn A. Starnes, S. Ram Kumar   +5 more
openalex   +2 more sources

3D Hydrogel Cell Cultures and Their Biomedical Applications

Advanced NanoBiomed Research, EarlyView.
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai, Arushi Manchanda, Sarah L. Higginbottom, Estrella Sanz Rodriguez, Richard Wilson, Eva Tomaskovic‐Crook, Jeremy M. Crook, Brett Paull   +7 more
wiley   +1 more source

Grown up congenital heart disease patient presenting for non cardiac surgery: anaesthetic implications [PDF]

, 2010
Congenital heart disease patients surviving to adulthood have increased over the years due to various reasons. These patients are admitted in the hospital for non cardiac surgeries and other procedures more often than normal adult population.
Akhtar, Mohammad Irfan, Hameedullah,, Hamid, Mohammad, Khan, Fazal Hameed, Khan, Mansoor Ahmed, Saleemullah,, Samad, Khalid   +6 more
core   +1 more source

Is there a relationship between surgical case volume and mortality in congenital heart disease services? A rapid evidence review [PDF]

, 2015
Louise Preston, Janette Turner, Andrew Booth, Colin O’Keeffe, Fiona Campbell, Amrita Jesurasa, Katy Cooper, Elizabeth Goyder   +7 more
openalex   +1 more source