Results 201 to 210 of about 241,043 (267)

Hyperhomocysteinemia and Vitamin B Deficiency as Potential Aggravating Factors in Huntington's Disease: A Prospective Monocentric Study

Movement Disorders, EarlyView.
Abstract Background Although not confirmed, some studies have suggested that elevated homocysteine levels are common in patients with Huntington's disease (HD). Its clinical relevance remains unclear. Objectives We aimed to assess vitamin B and homocysteine levels in HD patients and explore the relationships among hyperhomocysteinemia, vitamin B ...
Salomé Puisieux, Elise Pourié, Céline Bonnet, Lucie Hopes, Solène Frismand, Myriam Bronner, Virginie Roth, Marion Wandzel, Natacha Sloboda, Laetitia Lambert, Abderrahim Oussalah, Amélia Julien, Irina Rotaru, Rosa‐Maria Guéant‐Rodriguez, Jean Louis Guéant, Carine Bossenmeyer‐Pourié, Mathilde Renaud   +16 more
wiley   +1 more source

Outcomes after a first acute myocardial infarction in patients with or without congenital heart disease. [PDF]

Eur Heart J
Holmgren L, von Koch S, Andell P, Sörensson P, Christersson C, Trzebiatowska-Krzynska A, Fedchenko M, Mandelanakis Z, Johansson B, Mohammad MA, Hlebowicz J.   +10 more
europepmc   +1 more source

Late INa as a Therapeutic Target: New Strategies, Computational Modelling, Drug Development, and Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT The Nav1.5 channel, a major isoform of voltage‐gated sodium ion channel, is mainly found in ventricular cardiomyocytes, playing a key role in generating essential cardiac action potentials for normal heart rhythms. Mutations in Nav1.5 have been associated with severe heart conditions such as long QT syndrome, Brugada syndrome, cardiac ...
Arkapravo Chattopadhyay, Lynn C. Lunsonga, Peter E. Light, Khaled Barakat   +3 more
wiley   +1 more source

Early Neurodevelopmental Outcomes in Children With Congenital Heart Disease.

JAMA Netw Open
Seed M, Ilardi D, Rofeberg V, Ortinau C, Goldberg C, Reichle G, Bush L, Elhoff J, Lisanti AJ, Butcher J, Rollins C, Van Bergen A, Peyvandi S, Bucholz E, Cox S, Hampton L, Sanz J, Monteiro S, Tewar S, Allen K, Lee C, Glotzbach K, Alexander N, Bear L, Anton C, Sananes R, Ly L, Boucher G, Wolfe K, Edwards L, Willen E, Tan A, Ortega C, Sood E, Sadhwani A, Plant KC, Quigley L, Pliego J, Valles E, Hines A, Wypij D, Miller T.   +41 more
europepmc   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Applications of robotic catheter ablation in congenital heart disease. [PDF]

Front Pediatr
Khairy P, Ernst S.
europepmc   +1 more source

The adult congenital heart disease collaborative care model: Improving access with a care delivery innovation. [PDF]

Int J Cardiol Congenit Heart Dis
Kemble Luo AS, Park C, Ruiz R, Seto TB, Kemble SB, Bratincsak A.   +5 more
europepmc   +1 more source

Functional genomics in <i>Xenopus</i> identifies ARHGAP10 as a congenital heart disease and ciliopathy gene. [PDF]

iScience
Sochacka E, Hinson ST, Shook DR, DeSimone DW, Kulkarni SS.   +4 more
europepmc   +1 more source

ADAMTS4 is a serum biomarker for pulmonary arterial hypertension associated with congenital heart disease. [PDF]

Front Med (Lausanne)
Xiao G, Chen Y, Meng Y, Wang Z, Cai J, Cao Z, Zeng S, Liang W, Yu Y, Wang H, Nie L, Liu X, Liao Y.   +12 more
europepmc   +1 more source