Results 21 to 30 of about 241,043 (267)
The use of Macitentan in Fontan circulation: a case report
Background The Fontan circulation, a result of a palliative procedure in patients with single systemic ventricles, is defined by chronically elevated pulmonary vascular resistance.
Polyvios Demetriades +4 more
doaj +1 more source
Congenital heart disease in adults
andardiovascular system occur in 7–10 per 1000 live births (0.7–1%). 113 It is the commonest form of congenital disease and accounts for approximately 30% of the total burden of congenital disease. With a decline in the incidence of rheumatic heart disease, congenital heart disease has become the main cause of heart disease in children in the developed
D, Findlow, E, Doyle
openaire +2 more sources
Objective: The number of patients with congenitally corrected transposition of the great arteries (ccTGA) surviving to old age is increasing. This study therefore sought to characterize 'geriatric' systemic right ventricle (sRV) in terms of clinical ...
Ewa Kowalik +6 more
doaj +1 more source
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak +5 more
wiley +1 more source
PROSTAGLANDINS IN CONGENITAL HEART DISEASE [PDF]
Prior to the use of prostaglandins (PGE1) many infants with ductus arteriosus dependent congenital heart disease (CHD) born outside tertiary care centres did not survive the period from diagnosis to inter-hospital transportation for surgery. Development in the area of neonatal cardiac surgery has increased the importance of rapid diagnosis and ...
M, Sharma +3 more
openaire +2 more sources
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani +7 more
wiley +1 more source
Cardiac index in adults with repaired tetralogy of Fallot: Are we missing the forest for the trees?
Background: Many cardiac parameters have been associated with poor outcomes in patients with repaired tetralogy of Fallot (TOF) and significant residual pulmonary regurgitation (PR).
Maria Fadous +7 more
doaj +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source

