Results 81 to 90 of about 1,233,281 (362)

Genetic Basis for Congenital Heart Disease: Revisited: A Scientific Statement From the American Heart Association.

Circulation, 2018
This review provides an updated summary of the state of our knowledge of the genetic contributions to the pathogenesis of congenital heart disease. Since 2007, when the initial American Heart Association scientific statement on the genetic basis of ...
M. Pierpont, M. Brueckner, W. Chung, V. Garg, R. Lacro, A. McGuire, S. Mital, J. Priest, W. Pu, A. Roberts, S. Ware, B. Gelb, M. Russell   +12 more
semanticscholar   +1 more source

Advances in Conductive Nanomaterials for Cardiac Arrhythmia and Future Directions in Bioevaluation Strategies

Advanced Healthcare Materials, EarlyView.
Conductive nanomaterials (CNMs) show promising potential in cardiac tissue regeneration and restoring cardiac rhythm as reported in several in vitro studies. This review article elaborates on the applications of CNMs in the treatment of myocardial infarction (MI) and MI‐induced cardiac arrhythmias, and it sheds light on the innovative approach of ...
Sumithra Y. Srinivasan, Anna Laromaine
wiley   +1 more source

The contribution of pulse oximetry to the early detection of congenital heart disease in newborns [PDF]

, 2018
Approximately half of all newborns with congenital heart disease are asymptomatic in the first few days of life. Early detection of ductal-dependant cardiac malformations prior to ductal closure is, however, of significant clinical importance, as the ...
Arlettaz, Romaine, Bauersfeld, Urs, Bauschatz, Andrea Seraina, Essers, Bettina, Mönkhoff, Marion   +4 more
core  

Therapeutic Antibodies for Mosquito‐Borne Orthoflavivirus Infections: Discovery, Engineering Approaches, and Advances in mRNA‐Based Delivery Systems

Advanced Therapeutics, EarlyView.
This review explores how antibody engineering and display technologies are driving therapeutic advances against mosquito‐borne orthoflaviviruses such as Zika, dengue, and yellow fever viruses. It highlights diverse neutralizing targets on the envelope protein, including the conserved fusion loop, and discusses how Fc engineering, rational antigen ...
Ana Clara Barbosa Antonelli, Lucas Silva Rodrigues, Maria Clara Moura Pinheiro, Sylvia Barbosa Pinhate, Marcelo de Macedo Brígido, Andréa Queiroz Maranhão   +5 more
wiley   +1 more source

Case Report: Sustained ventricular arrhythmia in a child supported by a Berlin heart EXCOR ventricular assist device

Frontiers in Transplantation
Mechanical circulatory support is an established therapy to support failing hearts as a bridge to transplantation. Although tolerated overall, arrhythmias may occur after ventricular assist device implantation and can complicate patient management.
Diego Lineker Marquetto Silva, Stephanie Ondracek Lemouche, Tatiane Yukari Takahashi, Isadora de Campos Zanon, Adailson Siqueira, Desiree Machado, Estela Azeka, Sissy Lara de Melo   +7 more
doaj   +1 more source

Asuhan Keperawatan Pada An. N Dengan Gangguan Kardiovaskuler : Penyakit Jantung Bawaan Di Ruang Cempaka III RSUD Pandan Arang Boyolali [PDF]

, 2015
Background : Infant and child mortality rate caused by Congenital Heart Disease quite high in both developed countries and developing countries (including Indonesia).
, Agus Sudaryanto, S.Kep., Ns., M.Kes, Kurniawan, Risky Rahmat   +1 more
core  

Adenylosuccinate Synthase 1 Deficiency Improves Energy Metabolism by Promoting Adipose Tissue Re‐esterification via Glycerol Kinase Upregulation

Advanced Science, EarlyView.
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun, Miriayi Alimujiang, Wenfei Li, Shuqin Chen, Yingying Su, Tingting Hu, Xuhong Lu, Yafen Ye, Ningning Bai, Fan Hu, Xiaoya Li, Rongrong Xu, Jun Xu, Jiarui Zhao, Yan Lu, Xiaojing Ma, Ying Yang   +16 more
wiley   +1 more source

Endothelium in the pharyngeal arches 3, 4 and 6 is derived from the second heart field. [PDF]

, 2017
Oxygenated blood from the heart is directed into the systemic circulation through the aortic arch arteries (AAAs). The AAAs arise by remodeling of three symmetrical pairs of pharyngeal arch arteries (PAAs), which connect the heart with the paired dorsal ...
Astrof, Sophie, Chen, Dongying, Chen, Kelley, Jubran, Ali, Ramirez, AnnJosette, Wang, Xia   +5 more
core   +2 more sources

Real‐time cardiovascular MR with spatio‐temporal artifact suppression using deep learning–proof of concept in congenital heart disease [PDF]

Magnetic Resonance in Medicine, 2018
Real‐time assessment of ventricular volumes requires high acceleration factors. Residual convolutional neural networks (CNN) have shown potential for removing artifacts caused by data undersampling.
A. Hauptmann, S. Arridge, F. Lucka, V. Muthurangu, J. Steeden   +4 more
semanticscholar   +1 more source

Disruption of Gut Microbiota‐Mediated De Novo NAD+ Synthesis Contributes to the Development of Polycystic Ovary Syndrome

Advanced Science, EarlyView.
This study demonstrates that patients with PCOS exhibit altered gut microbial profiles, and FMT from PCOS patients induces PCOS‐like symptoms in mice. Specifically, gut dysbiosis reduces 3‐HAA levels in the context of PCOS. Administration of 3‐HAA to mice alleviates PCOS by promoting de novo NAD+ synthesis.
Ke Chen, Huafeng Geng, Yang Zheng, Hongyang Xie, Rui Qin, Junyang Chen, Cong Ye   +6 more
wiley   +1 more source