Results 31 to 40 of about 590,777 (216)

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Single‐Nucleus Atlas of Spinal Sarcopenia Patients Reveals Disruption of Quiescent and Regenerative Satellite Cell Niches in Fatty‐Infiltrated Muscle

Advanced Science, EarlyView.
Mechanisms of Fatty Infiltration and Muscle Degeneration. Clinical metadata identified intramuscular fat accumulation as an independent driver of muscle mass decline. Single‐nucleus RNA sequencing of spinal sarcopenia muscle revealed adipogenic reprogramming of fibro‐adipogenic progenitors, satellite‐cell niche disruption, and elevated levels of the ...
Wenkai Wu, Renxian Wang, Dingding Wang, Quanzhong Ren, Ling Wang, Fangfang Duan, Guihe Yang, Ruixuan Yu, Yi Wang, Yingyu Zhang, Zetong Zang, Chuqi Li, Weijia Liu, Wenshuang Zhang, Yi Yuan, Zitong Cheng, Xiaoguang Cheng, Junbo Liang, Yajun Liu   +18 more
wiley   +1 more source

ADNP‐Related Helsmoortel–Van der Aa Syndrome: A Review of the Literature and Clinical Recommendations for Assessment and Monitoring

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT ADNP‐related Helsmoortel–Van der Aa syndrome (ADNP‐related HVDAS) is a single gene form of autism spectrum disorder (ASD) caused by pathogenic sequence variants in the activity‐dependent neuroprotective protein (ADNP) gene. In addition to ASD, ADNP‐related HVDAS is associated with a wide range of cognitive, behavioral, and physical health ...
Jarrett Fastman, Ana Kolevzon, Paige Siper, Tess Levy, Jeffrey M. Saland, Yitzchak Frank, Robert Rapaport, Kayla Kupietzky, William E. Bennett Jr, Bruce Gelb, Sandra Bedrosian Sermone, Alexander Kolevzon   +11 more
wiley   +1 more source

Spontaneous correetlon In the congenital dlslocatlon of the hip

Acta Orthopaedica et Traumatologica Turcica, 2020
1 It was pointed out that the case of congenital hip dysplasia would be spontaneous correction in spite of treatment in the congenital dislocation of the hip has to be obtained by conservative and surgical procedures.\n2 Our case was reported to be ...
Selcuk Atilla
doaj  

The Ilizarov technology for closed reduction of hip dislocation in children with developmental hip dysplasia

Гений oртопедии, 2021
Introduction The possibility of gradual closed reduction of hip dislocation in children over 1.5 years old is considered doubtful. Purpose Analysis of long-term results of applying the Ilizarov technique of gradual closed reduction in combination with ...
Mikhail P. Teplenky, Evgenii V. Oleinikov, Vyacheslav S. Bunov   +2 more
doaj   +1 more source

Severe Headbanging Responsive to Levodopa in a Child With FOXP1 Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We report a 9‐year‐old female with FOXP1 syndrome due to a de novo in‐frame deletion in the FOXP1 gene. The child has a severe neurodevelopmental disorder including global developmental delay and autism spectrum disorder. At age 2, she developed severe headbanging, which was progressive and did not respond to multidisciplinary, behavioral ...
Pamela Veale, Christopher Tiessen, Vithya Gnanakumar   +2 more
wiley   +1 more source

The evaluation of the results of open reduction and innominate osteotomy via different methods in the treatment of congenital hip dislocation

Acta Orthopaedica et Traumatologica Turcica, 2020
Of 31 patients who underwent open reduction and innominate osteptomy due to congenital hip dislocation, 39 hips were assessed by means of Barrett. modified Severin and Trevar evaluation criteria.
Ömer Faruk Bilgen, Kemal Durak, Remzi Özerdemoğlu, Ufuk Aydınlı, Öner Gedikoğlu   +4 more
doaj  

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

Changes in the spino-pelvic balance after hip replacement in patients with congenital hip dislocation

Хирургия позвоночника, 2018
Objective. To analyze the features of the sagittal spino-pelvic balance formation in patients with congenital hip dislocation and its changes after total hip replacement with restoration of the rotation center. Material and Methods.
Lev S. Shnaider, Vitaly V. Pavlov, Aleksandr V. Krutko, Vyacheslav A. Bazlov, Tariel Z. Mamuladze, Aleksey V. Peleganchuk   +5 more
doaj  

Congenital dislocation of the knee complicated with bilateral hip dislocation: a case report and literature review

BMC Musculoskeletal Disorders
Background Congenital dislocation of the knee is characterised by excessive knee extension or dislocation and anterior subluxation of the proximal tibia, and this disease can occur independently or coexist with different systemic syndromes. Nevertheless,
Bohai Qi, Qiang Jie, Xiaowei Wang, Qingda Lu, Fei Su, Yating Yang   +5 more
doaj   +1 more source