Results 11 to 20 of about 630,874 (291)
A 7-year study on the prevalence of congenital hypothyroidism in northern Iran
Electronic Physician, 2018 Background: Congenital hypothyroidism (CH) is one of the most common congenital endocrine disorders. The present study determined the prevalence and demographic characteristics of congenital hypothyroidism in the north of Iran. Objective: To determine
Zahra Beheshti +4 more
doaj +2 more sources
Zebrafish duox mutations provide a model for human congenital hypothyroidism
Biology Open, 2019 Thyroid dyshormonogenesis is a leading cause of congenital hypothyroidism, a highly prevalent but treatable condition. Thyroid hormone (TH) synthesis is dependent on the formation of reactive oxygen species (ROS).
Kunal Chopra +2 more
doaj +2 more sources
Frontiers in Endocrinology, 2022 Preterm newborns are forced to adapt to harsh extrauterine conditions and endure numerous adversities despite their incomplete growth and maturity. The inadequate thyroid hormones secretion as well as the impaired regulation of hypothalamus-pituitary ...
Martyna Kłosińska +2 more
semanticscholar +1 more source
Genetics of congenital hypothyroidism: Modern concepts
Pediatric Investigation, 2022 Congenital hypothyroidism (CH) is the most common neonatal endocrine disorder and one of the most common preventable causes of intellectual disability in the world.
A. Stoupa +3 more
semanticscholar +1 more source
Congenital Hypothyroidism: Long-Term Growth and Intellectual Outcomes With a Lower Initial Levothyroxine Dose. [PDF]
Clin Endocrinol (Oxf)ABSTRACT Objectives This study aims to review the long‐term outcome of congenital hypothyroidism (CH) and whether patient‐ or treatment‐related factors impact the outcomes, especially focusing on the initial Levothyroxine dose. Methods This is a retrospective, cross‐sectional study of the children diagnosed with CH who received Levothyroxine at Ajou ...
Park JH, Oh JH, Cho MH, Shim YS, Lee HS.
europepmc +2 more sources
MECHANISMS IN ENDOCRINOLOGY: The pathophysiology of transient congenital hypothyroidism
European Journal of Endocrinology, 2022 Transient congenital hypothyroidism (TCH) refers to congenital hypothyroidism which spontaneously resolves in the first few months or years of life.
C. Peters, N. Schoenmakers
semanticscholar +1 more source
Guidelines for Newborn Screening of Congenital Hypothyroidism (2021 Revision)
Clinical Pediatric Endocrinology, 2022 . Purpose of developing the guidelines: Newborn screening (NBS) for congenital hypothyroidism (CH) was started in 1979 in Japan, and early diagnosis and treatment improved the intelligence prognosis of CH patients.
K. Nagasaki +9 more
semanticscholar +1 more source
Diagnosis and Management of Central Congenital Hypothyroidism
Frontiers in Endocrinology, 2021 Central congenital hypothyroidism (CH) is defined as thyroid hormone (TH) deficiency at birth due to insufficient stimulation by the pituitary of the thyroid gland. The incidence of central CH is currently estimated at around 1:13,000.
Peter Lauffer +4 more
semanticscholar +1 more source
Thyroid, 2020 Background: An ENDO-European Reference Network (ERN) initiative was launched that was endorsed by the European Society for Pediatric Endocrinology and the European Society for Endocrinology with 22 participants from the ENDO-ERN and the two societies ...
P. V. van Trotsenburg +21 more
semanticscholar +1 more source
Newborn Screening for Congenital Hypothyroidism in Japan
International Journal of Neonatal Screening, 2021 Congenital hypothyroidism (CH) is the most common preventable cause of intellectual impairment or failure to thrive by early identification and treatment.
K. Minamitani
semanticscholar +1 more source