Results 121 to 130 of about 3,875,802 (326)

Nanotherapy for Neural Retinal Regeneration

Advanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu, Li Dong, Yujia Lv, Xuhan Shi, Ruiheng Zhang, Wenda Zhou, Haotian Wu, Heyan Li, Yitong Li, Zhou Li, Dan Luo, Wen‐Bin Wei   +11 more
wiley   +1 more source

The SIR model in a moving population: propagation of infection and herd immunity [PDF]

arXiv, 2022
In a collection of particles performing independent random walks on $\mathbb Z^d$ we study the spread of an infection with SIR dynamics. Susceptible particles become infected when they meet an infected particle. Infected particles heal and are removed at rate $\nu$.
arxiv  

Miscarriage and stillbirth following maternal Zika virus infection in nonhuman primates. [PDF]

, 2018
Zika virus (ZIKV) infection is associated with congenital defects and pregnancy loss. Here, we found that 26% of nonhuman primates infected with Asian/American ZIKV in early gestation experienced fetal demise later in pregnancy despite showing few ...
Aagaard, Kjersti M, Adams Waldorf, Kristina M, Ardeshir, Amir, Bliss-Moreau, Eliza, Bohm, Rudolf P, Capuano, Saverio V, Chiu, Charles Y, Coffey, Lark L, Colgin, Lois M, Dudley, Dawn M, Friedrich, Thomas C, Gale, Michael, Gilbert, Margaret H, Golos, Thaddeus G, Grigsby, Peta L, Hirsch, Alec J, Hodge, Travis, Hotchkiss, Charlotte E, Keesler, Rebekah I, MacAllister, Rhonda P, Maness, Nicholas J, Martín, Claudia Sánchez-San, Mejia, Andres, Mohr, Emma L, O'Connor, David H, Panganiban, Antonito T, Patterson, Jean L, Pecoraro, Heidi L, Rajagopal, Lakshmi, Seferovic, Maxim, Simmons, Heather A, Steinbach, Rosemary J, Streblow, Daniel N, Tamhankar, Manasi, Tardif, Suzette, Van Rompay, Koen K, Veazey, Ronald S, Wang, Xiaolei   +37 more
core  

Characteristic and Correlation Between TIME and Complication After Destructive Eye Procedure Patient at Plastic and Reconstruction Division Sanglah Hospital\u27s Eye Clinic Bali-Indonesia [PDF]

, 2012
Destructive eye procedure can be carried out by enucleation, evisceration and excenteration. Some efforts have been developed to reduce the complications, but it still occur within several years after the operation.
Sukartini, D. (D), Triharpini, N. (N), Yuliawati, P. (P)   +2 more
core   +2 more sources

Long‐Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model

Advanced Science, EarlyView.
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du, Jun Huang, Aizhen Zhang, Fangfang Zhao, Tianwen Chen, Quinn M. McDermott, Tony Zheng, Haibo Wang, Rongli Zhang, Xiaolin Zhang, Jerome Allison, Hong Zhu, Wu Zhou, Qing Yin Zheng   +13 more
wiley   +1 more source

Development of novel vaccines against human cytomegalovirus

Human Vaccines & Immunotherapeutics, 2019
Congenital human cytomegalovirus (HCMV) infection and HCMV infection of the immunosuppressed patients cause significant morbidity and mortality, and vaccine development against HCMV is a major public health priority. Efforts to develop HCMV vaccines have
Xinle Cui, Clifford M. Snapper
doaj   +1 more source

Learning normal appearance for fetal anomaly screening: Application to the unsupervised detection of Hypoplastic Left Heart Syndrome [PDF]

arXiv, 2020
Congenital heart disease is considered as one the most common groups of congenital malformations which affects $6-11$ per $1000$ newborns. In this work, an automated framework for detection of cardiac anomalies during ultrasound screening is proposed and evaluated on the example of Hypoplastic Left Heart Syndrome (HLHS), a sub-category of congenital ...
arxiv  

Parasite infection in a cell population with deaths and reinfections [PDF]

arXiv, 2021
We introduce a model of parasite infection in a cell population, where cells can be infected, either at birth through maternal transmission, from a contact with the parasites reservoir, or because of the parasites released in the cell medium after the lyses of infected cells.
arxiv  

Hearing Loss With Congenital Cytomegalovirus Infection

Pediatrics, 2019
Incidence of hearing loss in children with cCMV infection is discussed, and risk indicators for hearing loss are described. OBJECTIVE: In this study, we determined the prevalence of hearing loss in 157 children with proven congenital cytomegalovirus ...
I. Foulon, Yannick De Brucker, R. Buyl, Elke Lichtert, K. Verbruggen, D. Piérard, Fleur A. Camfferman, L. Gucciardo, F. Gordts   +8 more
semanticscholar   +1 more source

Neutralization of Diverse Human Cytomegalovirus Strains Conferred by Antibodies Targeting Viral gH/gL/pUL128-131 Pentameric Complex [PDF]

, 2017
Human cytomegalovirus (HCMV) is the leading cause of congenital viral infection, and developing a prophylactic vaccine is of high priority to public health.
Adler, Stuart P., An, Zhiqiang, DePhillips, Pete A., Freed, Daniel C., Fu, Tong-Ming, Ha, Sha, Hamm, Melissa, Li, Fengsheng, Loughney, John W., McLellan, Jason S., McVoy, Michael A., Nickle, David C., Rustandi, Richard R., Tang, Aimin, Troutman, Matthew C., Vlasak, Josef, Wang, Dai, Wang, I-Ming, Zhang, Ningyan, Zhu, Hua   +19 more
core   +3 more sources