Results 61 to 70 of about 363,478 (240)

Human Cytomegalovirus Modifies Placental Small Extracellular Vesicle Composition to Enhance Infection of Fetal Neural Cells In Vitro

Viruses, 2022
Although placental small extracellular vesicles (sEVs) are extensively studied in the context of pregnancy, little is known about their role during viral congenital infection, especially at the beginning of pregnancy.
Mathilde Bergamelli, Hélène Martin, Yann Aubert, Jean-Michel Mansuy, Marlène Marcellin, Odile Burlet-Schiltz, Ilse Hurbain, Graça Raposo, Jacques Izopet, Thierry Fournier, Alexandra Benchoua, Mélinda Bénard, Marion Groussolles, Géraldine Cartron, Yann Tanguy Le Gac, Nathalie Moinard, Gisela D’Angelo, Cécile E. Malnou   +17 more
doaj   +1 more source

Microcephaly and macrocephaly. A study on anthropometric and clinical data from 308 subjects [PDF]

, 2019
Head circumference is the auxological parameter that most correlates with developmental anomalies in childhood. Head circumference (HC) two standard deviations (SD) below or above the mean defines microcephaly and macrocephaly, respectively.
Corsello G., Mancuso G., Martorana C., Montante C., Notarbartolo V., Piro E., Schierz I. A. M., Vanella V.   +7 more
core   +1 more source

Lattice Structures for Bone Replacement: The Intersection of Bone Biomechanics, Lattice Design, and Additive Manufacturing

Advanced Materials Technologies, EarlyView.
This review outlines how understanding bone's biology, hierarchical architecture, and mechanical anisotropy informs the design of lattice structures that replicate bone morphology and mechanical behavior. Additive manufacturing enables the fabrication of orthopedic implants that incorporate such structures using a range of engineering materials ...
Stylianos Kechagias, Maxwell J. Munford, Frederik C.H. Masure, Richard J. van Arkel, Reece N Oosterbeek   +4 more
wiley   +1 more source

Controversial questions of medical statistical registration of congenital infections

Журнал инфектологии, 2014
Medical aid improvement in the cases of congenital infections (CI) is one of the most important problems in modern obstetrics and perinatology. The true incidence of congenital infections is not known. One of the reasons for this situation is the lack of
I. G. Tekhova, M. G. Dariina, K. N. Movchan, N. M. Khrustaleva, Yu. V. Gorelik, K. I. Rusakevich   +5 more
doaj   +1 more source

Cytomegalovirus and Epstein–Barr Virus Associations with Neurological Diseases and the Need for Vaccine Development

Vaccines, 2020
Herpesviruses have been isolated from a wide range of hosts including humans—for which, nine species have been designated. The human herpesviruses are highly host adapted and possess the capacity for latency, allowing them to survive in the host ...
Peter A. C. Maple
doaj   +1 more source

Cortical Auditory Evoked Potentials in Children with Prenatal Exposure to Zika Virus

Viruses, 2022
Prenatal exposure to ZIKV can cause neurologic and auditory damage. The electrophysiological responses obtained by Cortical Auditory Evoked Potentials (CAEP) may provide an objective method to investigate the function of cortical auditory pathways in ...
Laís Cristine Delgado da Hora, Lilian Ferreira Muniz, Leonardo Gleygson Angelo Venâncio, Karina Paes Advíncula, Jéssica Dayane da Silva, Diana Babini Lapa de Albuquerque Britto, Demócrito de Barros Miranda Filho, Elizabeth B. Brickley, Ricardo Arraes de Alencar Ximenes, Silvio da Silva Caldas Neto, Mariana de Carvalho Leal   +10 more
doaj   +1 more source

Estimation of the worldwide seroprevalence of cytomegalovirus : a systematic review and meta-analysis [PDF]

, 2019
Cytomegalovirus (CMV) infection does not usually produce symptoms when it causes primary infection, reinfection, or reactivation because these three types of infection are all controlled by the normal immune system.
Anderholm, Arvin, Bate, Boeckh, Buerkner, Cannon, Cannon, Deayton, Emery, Gkrania-Klotsas, Griffiths, Griffiths, Guerra, Hyde, Institute of Medicine Committee to Study Priorities for Vaccine Development, Kempen, Kenneson, Kharfan-Dabaja, Lilleri, Marty, Moher, Pass, Pembrey, Plotkin, Revello, Richardson, Rubin, Sabbaj, Simanek, Slyker, Vries, Wimperis   +31 more
core   +2 more sources

A Soft Robotic Device for Targeted Massage Therapy of Residual Limbs

Advanced Robotics Research, EarlyView.
Residual limb edema after amputation can hinder recovery and delay prosthetic fitting. This study presents a soft‐robotic wearable device that delivers sequential compression through pneumatic McKibben actuators. By replicating the principles of manual lymphatic drainage, the device generates controlled mechanotherapeutic pressure patterns, providing a
Maria Grazia Polizzotto, Alessio Capecchi, Maartje Van der Lingen, Emanuele Gruppioni, Arianna Menciassi, Linda Paternò   +5 more
wiley   +1 more source

Perturbation of B Cell Gene Expression Persists in HIV-Infected Children Despite Effective Antiretroviral Therapy and Predicts H1N1 Response

Frontiers in Immunology, 2017
Despite effective antiretroviral therapy (ART), HIV-infected individuals with apparently similar clinical and immunological characteristics can vary in responsiveness to vaccinations. However, molecular mechanisms responsible for such impairment, as well
Nicola Cotugno, Nicola Cotugno, Lesley De Armas, Suresh Pallikkuth, Stefano Rinaldi, Stefano Rinaldi, Biju Issac, Alberto Cagigi, Alberto Cagigi, Paolo Rossi, Paolo Rossi, Paolo Palma, Savita Pahwa   +12 more
doaj   +1 more source

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

Advanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She, Rui Liu, Chen Fang, Shuyu Zhang, Yizhi Hu, Fei Guo, Yuhang Long, Mengzhen Ding, Haiyan Wu, Bokang Zhou, Zexin Yang, Ying Jiang, Jianzhong Sheng, Ling Gao, Hefeng Huang   +14 more
wiley   +1 more source