Results 61 to 70 of about 2,057,508 (290)

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Birth prevalence and characteristics of congenital cytomegalovirus infection in an urban birth cohort, Jakarta, Indonesia

International Journal of Infectious Diseases, 2019
Objectives: Little is known about the birth prevalence and characteristics of congenital cytomegalovirus (CMV) infection in developing countries. To determine the prevalence and characteristics of congenital CMV infection in Indonesia, we conducted a ...
Nina Dwi Putri, Ageng Wiyatno, Rama Dhenni, Ida Yus Sriyani, Aghnianditya Kresno Dewantari, Setyo Handryastuti, Adhi Teguh Perma Iskandar, Meka Medina Rahma, Niphidiah Jumiyanti, Yuni Yudha Aprilia, Ari Prayitno, Mulya Rahma Karyanti, Hindra Irawan Satari, Sri Rezeki Hadinegoro, Khin Saw Aye Myint, Dodi Safari   +15 more
doaj   +1 more source

From Fetal to Neonatal Neuroimaging in TORCH Infections: A Pictorial Review

Children, 2022
Congenital infections represent a challenging and varied clinical scenario in which the brain is frequently involved. Therefore, fetal and neonatal neuro-imaging plays a pivotal role in reaching an accurate diagnosis and in predicting the clinical ...
Giulia Lucignani, Alessia Guarnera, Maria Camilla Rossi-Espagnet, Giulia Moltoni, Amanda Antonelli, Lorenzo Figà Talamanca, Chiara Carducci, Francesca Ippolita Calo Carducci, Antonio Napolitano, Carlo Gandolfo, Francesca Campi, Cinzia Auriti, Cecilia Parazzini, Daniela Longo   +13 more
doaj   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

Screening for Congenital Cytomegalovirus Infection in Newborns

Viruses
Congenital cytomegalovirus infection is an underrecognized congenital infection. Globally, it impacts approximately 1 of every 200 live births. Although infected infants can have an increased risk of long-term sequelae, such as neurodevelopmental ...
Junfeng Zhang, Jiajia Cao, Qing Ye
doaj   +1 more source

Congenital Chylothorax with Cytomegalovirus Positivity: An Etiological Dilemma in a Neonate with Non-Immune Hydrops Fetalis

Indian Pediatrics Case Reports, 2023
Background: Nonimmune hydrops fetalis (NIHF) due to congenital chylothorax (CC) is rare and is usually associated with high mortality. Chylothorax complicated with congenital cytomegalovirus (CMV) infection is extremely rare and the management becomes ...
Yash Jain, Shivani Jain, Jenisha Jain, Minakshi Sharma   +3 more
doaj   +1 more source

Passive immunization during pregnancy for congenital cytomegalovirus infection

, 2005
BACKGROUND: Currently, there is no effective intervention for a primary cytomegalovirus (CMV) infection during pregnancy. METHODS: We studied pregnant women with a primary CMV infection.
Giuseppe Gentile, Congenital Cytomegalovirus Collaborating Group, Al M. Best, Giovanni Nigro, Stuart P. Adler, Renato La Torre   +5 more
core   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Human Cytomegalovirus Modifies Placental Small Extracellular Vesicle Composition to Enhance Infection of Fetal Neural Cells In Vitro

Viruses, 2022
Although placental small extracellular vesicles (sEVs) are extensively studied in the context of pregnancy, little is known about their role during viral congenital infection, especially at the beginning of pregnancy.
Mathilde Bergamelli, Hélène Martin, Yann Aubert, Jean-Michel Mansuy, Marlène Marcellin, Odile Burlet-Schiltz, Ilse Hurbain, Graça Raposo, Jacques Izopet, Thierry Fournier, Alexandra Benchoua, Mélinda Bénard, Marion Groussolles, Géraldine Cartron, Yann Tanguy Le Gac, Nathalie Moinard, Gisela D’Angelo, Cécile E. Malnou   +17 more
doaj   +1 more source