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Congenital insensitivity to pain with anhidrosis
Muscle & Nerve, 1980AbstractA nine‐year‐old child presented with congenital insensitivity to pain and anhidrosis. Quantitative studies and electron microscopy of the cutaneous branch of the radial nerve revealed almost complete absence of small myelinated and unmyelinated fibers and a disproportionate number of nerve fibers with a diameter of 6–10 μm.
E, Rafel +4 more
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CONGENITAL INSENSITIVITY TO PAIN WITHOUT ANHIDROSIS
Khyber Journal of Medical Sciences, 2023Congenital Insensitivity to Pain (CIP) is a condition present from birth that inhibits the ability to perceive physical pain. Affected individuals are unable to feel pain in any part of their body. Although they feel discriminative touch, patients are unable to perceive what any person with a normal functioning sensory and autonomic nervous system ...
Arshad Khan +3 more
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Congenital insensitivity to pain: an update
Pain, 2003Elna M. Nagasako, Anne Louise Oaklander, Robert H. Dworkin* Washington University School of Medicine, St. Louis, MO, USA Nerve Injury Unit, Departments of Anesthesiology, Neurology, and Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA Department of Anesthesiology, University of Rochester School of Medicine and ...
Elna M, Nagasako +2 more
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Congenital insensitivity to pain with anhidrosis
Pediatric Neurology, 2001Congenital insensitivity to pain with anhidrosis is an autosomal-recessive disorder resulting from defective neural crest differentiation with loss of the first-order afferent system, which is responsible for pain and temperature sensation. There is also a neuronal loss in the sympathetic ganglia. Lack of sweating, hyperthermia, and infections of bones
L, Sztriha +4 more
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[Congenital insensitivity to pain].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2014Congenital insensitivity to pain belongs to rare diseases called hereditary sensory neuropathy (HSN). The disturbance of sense and secondary harms are creating clinical picture. The aim of this report was to describe therapeutic problems with which we met with a three siblings with congenital insensitivity to pain.
Janusz, Popko +2 more
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Congenital insensitivity to pain in one family
Journal of Pediatric Orthopaedics B, 2018Congenital insensitivity to pain (CIP) is a rare autosomal recessive genetic disease caused by mutation in several different genes. The diagnosis requires the combined skills and cooperation of pediatricians, neurologists, radiologists, pathologists, and orthopedic surgeons.
Andrey, Svec +2 more
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[Congenital insensitivity to pain].
Revue neurologique, 2009Congenital insensitivity to pain (CIP) is a rare syndrome with various clinical expressions, characterized by a dramatic impairment of pain perception since birth. In the 1980s, progress in nerve histopathology allowed to demonstrate that CIP was almost always a manifestation of hereditary sensory and autonomic neuropathies (HSAN) involving the small ...
N, Danziger, J-C, Willer
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Orthopedic Aspects of Congenital Insensitivity to Pain
Clinical Orthopaedics and Related Research, 1983In an 11-year-old girl with congenital insensitivity to pain, diagnosis depended on three diagnostic features: pain sensation absent from birth; entire body affected; all other sensory modalities and deep tendon reflexes present. The cause of this disease is unknown.
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CONGENITAL UNIVERSAL INSENSITIVITY TO PAIN
Brain, 1960D W, BAXTER, J, OLSZEWSKI
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Congenital insensitivity to pain with anhidrosis
Annals of Neurology, 2015Thomas D, Bird, Phillip D, Swanson
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