Results 81 to 90 of about 8,700 (250)
Therapeutic opportunities for targeting cold pain pathways [PDF]
, 2015 Cold pain is a frequent symptom in neuropathic pain. Compared to other pain modalities, such as heat pain, the mechanisms behind physiological and pathological cold pain remain elusive.
Lewis, Richard J. +3 more
core +1 more source
Congenital insensitivity to pain with anhidrosis [PDF]
International Orthopaedics, 1998 PubMedID ...
Herdem M. +3 more
openaire +1 more source
Pain Practice, Volume 26, Issue 4, April 2026.ABSTRACT Introduction Complementary, alternative, and integrative medicine (CAIM) has gained popularity among patients experiencing pain, used alongside conventional medical treatments. This study aimed to explore the perceptions of pain clinicians and researchers on CAIM interventions.
Jeremy Y. Ng +2 more
wiley +1 more source
iNew Medicine, Volume 2, Issue 1, March 2026.This review traces the evolution of functional biliary stents, outlining the paradigm shift from “active intervention” strategies that target stent failure to next‐generation “enabling platforms.” These platforms leverage biodegradable materials, 3D/4D printing, and smart sensors to achieve personalized, regenerative, and theranostic solutions ...
Muhan Li +4 more
wiley +1 more source
Congenital Insensitivity to Pain without Anhidrosis: Orodental Problems and Management
Case Reports in Dentistry, 2015 This paper reports the case of a 4-year-old male patient who was brought by parents requesting for replacement of multiple missing anterior teeth. The patient suffered from congenital insensitivity to pain without anhidrosis and presented with full blown
N. Abdullah +2 more
doaj +1 more source
Hypnotic analgesia reduces brain responses to pain seen in others. [PDF]
, 2017 Brain responses to pain experienced by oneself or seen in other people show consistent overlap in the pain processing network, particularly anterior insula, supporting the view that pain empathy partly relies on neural processes engaged by self ...
A Krishnan +31 more
core +4 more sources
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, Volume 16, Issue 2, Page 252-267, February 2026.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
, 2018 I argue that the state of boredom (i.e., the transitory and non-pathological experience of boredom) should be understood to be a regulatory psychological state that has the capacity to promote our well-being by contributing to personal growth and to the ...
Elpidorou, Andreas
core
European Journal of Pain, Volume 30, Issue 2, February 2026.ABSTRACT Background Chronic pain, which is often unrelated to ongoing injury, is poorly understood and difficult to treat. Genetic studies have identified voltage‐gated sodium (Nav) channels, particularly gain‐of‐function mutations such as L858F and R1150W in human NaV1.7, as involved in the development of chronic pain. Methods A chronic pain model was
Serena Mares Malta +7 more
wiley +1 more source
Nature Communications, 2020 Loss of function of Nav1.7 leads to congenital insensitivity to pain in humans. Here the authors found that activation of Nav1.9 can restore nociception in Nav1.7 knockout mice, revealed by a venom-derived peptide as a probe.
Xi Zhou +14 more
doaj +1 more source