Results 61 to 70 of about 96,208,754 (165)
Health Screening and Post‐Arrival Services for Refugee Children From Afghanistan
Journal of Paediatrics and Child Health, Volume 62, Issue 8, Page 1403-1410, August 2026.ABSTRACT Aim To examine refugee health screening and services for Afghan children in the unique context of emergency expedited humanitarian resettlement in Melbourne, Australia. Methods Retrospective audit of Afghan children who attended a specialist child refugee health service between August 2021–April 2024. Results Participants included 218 children
Amy Williamson +5 more
wiley +1 more source
Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment
MedComm, Volume 7, Issue 4, April 2026.Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai +3 more
wiley +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, Volume 16, Issue 2, Page 252-267, February 2026.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
A Study of 29 Pediatric Patients With Osteomyelitis Resulting From Neuropathy and Pressure Effects
Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.Background Pediatric osteomyelitis secondary to underlying neuropathies is a rare, complex, but clinically severe entity. Loss of protective pain sensation and proprioception predisposes children to repetitive unperceived microtrauma and chronic pressure ulceration, facilitating insidious progression to deep bone infection.
Fatma Kılınç +5 more
wiley +1 more source
A case report of congenital insensitivity to pain and anhidrosis
, 2016 Congenital insensitivity to pain with anhidrosis (CIPA) is a rare disorder characterized by episodes of fever and pain insensitivity despite the fact that all other sensory modalities remain intact or minimally impaired.
Feroza Fatima +8 more
core +1 more source
Novel mutations in Chinese patients with congenital insensitivity to pain with anhidrosis
Molecular Pain, 2018 Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autosomal recessive disorder, characterized by loss of algesthesis and inability to sweat. CIPA is known to be caused by mutations in the neurotrophic tyrosine kinase receptor type 1 gene (
Xingzhu Geng +7 more
doaj +1 more source
Role of NTRK Fusion Genes in the Tumor Immune Microenvironment of HPV (+/−) Cervical Cancer
Journal of Medical Virology, Volume 97, Issue 8, August 2025.ABSTRACT Cervical cancer, a prevalent gynecological malignancy, is primarily associated with human papillomavirus (HPV) infection. However, some cases display distinct molecular alterations beyond HPV, significantly impacting the tumor immune microenvironment (TIME) and posing therapeutic challenges.
Qiongying Wang +7 more
wiley +1 more source
Nerve Growth Factor and the Physiology of Pain: Lessons from Congenital Insensitivity to Pain with Anhidrosis [PDF]
, 2012 application/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdf論文(Article)Congenital insensitivity to pain with anhidrosis (CIPA) is an autosomal recessive genetic disorder characterized by insensitivity to pain, anhidrosis ...
インドウ, ヤスヒロ +4 more
core +1 more source
Effectiveness of Total Hip Arthroplasty Combined With Hip Braces for Hip Charcot Arthropathy
Orthopaedic Surgery, Volume 17, Issue 3, Page 790-800, March 2025.This study evaluates the efficacy of Total Hip Arthroplasty combined with Hip Braces in patients with Charcot arthropathy. Assessment indicators such as VAS score, Oxford Hip Score, and UCLA score demonstrate significant improvements in hip joint function post‐surgery. Key complications include hip dislocation and acetabular component loosening.
Long‐Teng Chao +8 more
wiley +1 more source