Results 91 to 100 of about 23,188 (240)

Linkage Evidence for a Two-Locus Inheritance of LQT-Associated Seizures in a Multigenerational LQT Family With a Novel KCNQ1 Loss-of-Function Mutation [PDF]

, 2019
Mutations in several genes encoding ion channels can cause the long-QT (LQT) syndrome with cardiac arrhythmias, syncope and sudden death. Recently, mutations in some of these genes were also identified to cause epileptic seizures in these patients, and
Gessner, Guido, Heinemann, Stefan H., Prüss, Harald, Rimpau, Wilhelm, Ruppert, Ann-Katrin, Rüschendorf, Franz, Sander, Thomas, Schulz, Herbert   +7 more
core   +2 more sources

Benefits of Implantable Cardioverter–Defibrillator for Secondary Prevention in Patients With Organic Heart Disease

Annals of Noninvasive Electrocardiology, Volume 31, Issue 1, January 2026.
Three‐quarters of patients who underwent ICD/CRT‐D implantation for secondary prevention received appropriate ICD therapy and survived at least 1 year thereafter. In contrast, patients aged 70 or older and those with a history of ventricular fibrillation (VF) were less likely to benefit from secondary prevention with an ICD.
Rie Akagawa, Sou Otsuki, Minori Sakurazawa, Atsushi Kato, Hironori Furuse, Naomasa Suzuki, Yasuhiro Ikami, Yuki Hasegawa, Masaomi Chinushi, Takayuki Inomata   +9 more
wiley   +1 more source

Epicardially placed implantable cardioverter-defibrillator for a child with congenital long QT syndrome

Journal of Arrhythmia, 2017
A 7-year-old boy presented at our hospital with syncope. At birth, electrocardiography had shown a long QT interval with torsade de pointes (TdP). Congenital long QT syndrome (LQTS) had been diagnosed by genetic testing, and was successfully controlled ...
Hirotaro Sugiyama, MD, Motomi Tachibana, MD, Hiroshi Morita, MD, Nobuhiro Nishii, MD, Akihito Miyoshi, MD, Hiroyasu Sugiyama, MD, Koji Nakagawa, MD, Atsuyuki Watanabe, MD, Kazufumi Nakamura, MD, Hiroshi Ito, MD   +9 more
doaj   +1 more source

The importance of the epinephrine provocation test for the hidden type-1 congenital long QT syndrome

Türk Kardiyoloji Derneği Arşivi, 2020
Congenital long QT syndrome (LQTS) is a genetic channelopathy associated with a high incidence of sudden cardiac death in children and young adults. QT interval prolongation is typically the primary finding on the electrocardiography (ECG) recordings ...
Adem Atici, Ramazan Asoğlu, Hasan Ali Barman, Irfan Sahin   +3 more
doaj   +1 more source

Methods of Assessment and Clinical Relevance of QT Dynamics [PDF]

, 2005
The dependence on heart rate of the QT interval has been investigated for many years and several mathematical formulae have been proposed to describe the QT interval/heart rate (or QT interval/RR interval) relationship. While the most popular is Bazett’s
Agata, Musialik-Lydka, Anna, Sliwinska, Beata, Sredniawa, Piotr, Jarski, Zbigniew, Kalarus   +4 more
core  

Sex Hormones and Repolarization Dynamics During the Menstrual Cycle in Women Treated With QT‐Prolonging Drugs

Annals of Noninvasive Electrocardiology, Volume 31, Issue 1, January 2026.
Sex hormones significantly influence ventricular repolarization in women treated with QT‐prolonging drugs, with estrogen prolonging and progesterone/testosterone shortening QT measures. These findings highlight a hormonal mechanism for sex‐specific arrhythmia risk and support closer monitoring of reproductive‐age women receiving QT‐prolonging therapies.
Aneliya San, Ilan Goldenberg, Arwa Younis, Kris Cutter, Scott McNitt, Nona Sotoodehnia, Peter J. Kudenchuk, Thomas D. Rea, Dan E. Arking, Bronislava Polonsky, Wojciech Zareba, Mehmet Kemal Aktaş   +11 more
wiley   +1 more source

Hyperpyrexia associated with congenital Long QT Syndrome

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2014
Congenital long QT syndrome (CLQTS) is a genetic disorder presented with prolonged QT interval. In these patients, risk of sudden cardiac death due to ventricular tachyarrhythmias is high.
Nuriye Tarakci, Murat Konak, Huseyin Altunhan, Hayrullah Alp, Rahmi Ors   +4 more
doaj  

Pharmacotherapy Risks in Rare Genetic Diseases: Cross‐Referencing ACMG Secondary Findings v3.2 List With Clinical Databases

Clinical and Translational Science, Volume 19, Issue 1, January 2026.
ABSTRACT Clinical genomics and pharmacogenomics have largely remained separate fields, though some genetic variants have overlapping disease risk and drug implications. However, the extent of this overlap is not well studied. To explore this gap, we cross‐referenced genes from the American College of Medical Genetics Secondary Findings v3.2 list with ...
Josiah D. Allen, Benjamin Q. Duong, Jordan Brady, Pamela Arn   +3 more
wiley   +1 more source

Long QT interval in resting electrocardiogram – and what next? Sports cardiologist’s pointofview. Part 1. From electrophysiology to diagnostics

Pediatria i Medycyna Rodzinna, 2014
Electrocardiography is the most common and available cardiovascular diagnostic procedure and an important tool in everyday clinical practice of a family physician. Electrocardiogram interpretation is therefore an invaluable clinical skill.
Zbigniew Krenc
doaj   +1 more source

Electrical Storms in Brugada Syndrome: Review of Pharmacologic and Ablative Therapeutic Options [PDF]

, 2005
Electrical storm occurring in a patient with the Brugada syndrome is an exceptional but malignant and potentially lethal event. Efficient therapeutic solutions should be known and urgently applied because of the inability of usual antiarrhythmic means in
Haïssaguerre, M, Hocini, M, Maury, P
core   +2 more sources