Results 31 to 40 of about 1,357,879 (180)

Case based rubella surveillance in Abia State, South East Nigeria, 2007–2011 [PDF]

PeerJ, 2014
Introduction. Rubella infection has the potential of causing severe fetal birth defects collectively called congenital rubella syndrome (CRS) if the mother is infected early in pregnancy.
Chukwuemeka Anthony Umeh, Stella Chioma Onyi   +1 more
doaj   +2 more sources

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

The status of rubella IgG antibody titer between antenatal and postnatal among pregnant non-immune to rubella

Human Vaccines & Immunotherapeutics, 2021
Background: The infection of rubella in pregnancy is worrisome due to the fact that it causes miscarriages, congenital defects, and Congenital Rubella Syndrome (CRS).
Irfana Rasool, Ayesha Azad, Saeed Baradwan, Muhammad Salman Bashir, Dania Al-Jaroudi   +4 more
doaj   +1 more source

First Report of Uniparental Isodisomy of Chromosome 15 Revealing Angelman Syndrome and Microphthalmia Associated With a Novel Homozygous ALDH1A3 Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Paternal isodisomy of chromosome 15 (iUPD15) is a recognized cause of Angelman syndrome (AS), accounting for approximately 2%–5% of cases. Additionally, another recognized consequence of iUPD is the unmasking of autosomal recessive disorders. However, reports of recessive disorders resulting from iUPD15 remain scarce in the literature.
Gabriela Roldão Correia‐Costa, Joana Rosa Marques Prota, Antonia Paula Marques‐de‐Faria, Carlos Eduardo Steiner, Társis Paiva Vieira   +4 more
wiley   +1 more source

Radial outer retina reflectivity (RORR) sign in LAMP2‐associated retinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To describe the radial outer retina reflectivity (RORR) sign in patients carrying pathogenic variants in the X‐linked lysosome‐associated membrane protein‐2 (LAMP2) gene and to review the histologic characteristics of LAMP2 expression in the human retina.
Rachael C. Heath Jeffery, Bohdan Kousal, Ulrike Grünert, Christine A. Curcio, Svetlana Cherepanoff, Tina M. Lamey, Michel Michaelides, Chrysanthi Tsika, Isabelle Chow, Omar A. Mahroo, Seungmin Lee, Martin Meliska, Milos Kubanek, Jakub Sikora, Siying Lin, Raymond C. B. Wong, Petra Liskova, Fred K. Chen   +17 more
wiley   +1 more source

Congenital rubella syndrome and its protean manifestation in Nigeria

Egyptian Pediatric Association Gazette
Background Congenital rubella syndrome (CRS) arises from intrauterine infections with the rubella virus especially during the first trimester of pregnancy. It affects various systems resulting in disastrous outcomes.
Nubwa Yusufu Papka, Chinwe Chioma Okoro, Esther Anani, Maryam Abdulrahman Raji, Josephat M. Chinawa   +4 more
doaj   +1 more source

Mass measles rubella immunization campaign: Bhutan experience

Indian Journal of Community Medicine, 2011
Background: Bhutan has attained universal child immunization since 1991. Since then, immunization coverage is maintained at high level through routine immunization, periodic National Immunization Days, and mop up campaigns.
Bhakta R Giri, Pem Namgyal, K P Tshering, K P Sharma, Tandin Dorji, Chewang Tamang   +5 more
doaj   +1 more source

Modelling Impact of Different Varicella Immunisation Strategies Upon Introduction in the Swedish National Programme

Acta Paediatrica, EarlyView.
ABSTRACT Aim Countries with varicella immunisation programmes have seen major reductions in disease burden. While two‐dose schedules are now universally adopted, dosing ages vary, and some countries initially include catch‐up vaccination of older children to speed impact. This modelling study assessed three two‐dose schedules in the Swedish setting (1)
Gianpaolo Scalia Tomba, Frida Kasteng, Annika Ersson, Sören Andersson, Emma Appelqvist, Marie Nordahl, Kari Johansen   +6 more
wiley   +1 more source

Pathogenesis of Congenital Rubella Virus Infection in Human Fetuses: Viral Infection in the Ciliary Body Could Play an Important Role in Cataractogenesis

EBioMedicine, 2015
Background: Development of congenital rubella syndrome associated with rubella virus infection during pregnancy is clinically important, but the pathogenicity of the virus remains unclear.
Thong Van Nguyen, Van Hung Pham, Kenji Abe   +2 more
doaj   +1 more source

Epidemiological investigation and prevention and control strategies of rubella in Anhui province, China, from 2012 to 2021

Frontiers in Public Health, 2022
BackgroundRubella is a highly contagious viral infection with mild manifestations that occurs most often in children and young adults. Infection during pregnancy, especially during the first trimester, can result in an infant born with congenital rubella
Ning Zhang, Xiaodong Cheng, Shujie Zhou, Binbing Wang, Xianwei Luo, Yu Chai, Jihai Tang, Bin Su, Zhirong Liu   +8 more
doaj   +1 more source