Results 41 to 50 of about 11,146 (132)

Rpf‐Toxo: A Preliminary Computationally Designed Dense Granule Antigen‐Based Multi‐Epitope Vaccine Against Toxoplasma gondii

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This graphical abstract summarizes the in silico design of the multi‐epitope vaccine candidate Rpf‐Toxo (Seq4) against Toxoplasma gondii. The workflow includes antigen selection, epitope mapping, vaccine construction, structural and immunological evaluation, toll‐like receptor‐4 docking, immune simulation, safety assessment, codon optimisation and ...
Mohamad Hosein Safari, Seyyed Amir Hosseini, Shadan Ghiabi, Shamim Ghiabi, Davood Siamian, Hamidreza Majidiani, Hamid Irannejad, Ali Asghari   +7 more
wiley   +1 more source

Congenital Heart Disease Associated With Genetic Syndromes and Extracardiac Anomalies: A Six‐Year Epidemiological Study in a Brazilian Referral Center

Birth Defects Research, Volume 118, Issue 8, August 2026.
ABSTRACT Background Congenital heart diseases (CHDs) are structural and/or functional abnormalities of the heart that arise during embryonic cardiovascular development. They are the most common type of congenital defect and represent a major cause of neonatal morbidity and mortality, particularly when associated with genetic syndromes or other ...
Letícia Cordeiro Rodriguez, Nicole Lerner, Maria de Fátima Monteiro Pereira Leite, Carla Verona Barreto Farias, Michail Barmpas, Dulce Helena Gonçalves Orofino, Juan Clinton Llerena Junior   +6 more
wiley   +1 more source

CONGENITAL TOXOPLASMOSIS: CLINICAL COURSE AND RESIDUAL OUTCOMES

Детские инфекции (Москва), 2015
We examined 69 infants with clinically manifested forms of congenital toxoplasmosis diagnosed in theStavropolregion in the period from 1992 to 2012. The clinical course was characterized by a predominance of severe forms of congenial toxoplasmosis, high ...
L. Yu. Barycheva, M. V. Golubeva, M. A. Kabulova, I. V. Kostornaya   +3 more
doaj   +1 more source

Toxoplasma gondii‐Derived Soluble Factors Induce G2/M Phase Accumulation and p53‐Associated Mitochondrial Apoptosis in Human Umbilical Cord Mesenchymal Stem Cells

Journal of Cellular and Molecular Medicine, Volume 30, Issue 16, August 2026.
ABSTRACT Toxoplasma gondii infection poses potential risks to stem cell‐based therapeutic applications; however, the effects of parasite‐derived soluble factors on mesenchymal stem cells remain unclear. Here, we investigated the impact of T. gondii‐derived soluble factors (Tg‐SFs) on human umbilical cord‐derived mesenchymal stem cells (hUC‐MSCs).
Wei Zhou, Tingyu Chen, Ziping Yang, Jinjing Huang, Xinyi Lai, Jie Liu, Jiaqi Chu, Juanhua Quan   +7 more
wiley   +1 more source

Toxoplasmosis in pregnancy: a clinical, diagnostic, and epidemiological study in a referral hospital in Rio de Janeiro, Brazil

Brazilian Journal of Infectious Diseases, 2020
Toxoplasmosis in pregnant women can cause significant morbidity and mortality in the fetus, which may be mitigated by early diagnosis and treatment. Social factors have also been related to the risk of developing the congenital form of toxoplasmosis ...
Bianca Balzano De La Fuente Villar, Elizabeth de Souza Neves, Virginia Clare Louro, Juliana Frazão Lessa, Danielle Nascimento Rocha, Leonardo Henrique Ferreira Gomes, Saint Clair Gomes Junior, José Paulo Pereira, Junior, Maria Elisabeth Lopes Moreira, Letícia da Cunha Guida   +9 more
doaj   +1 more source

From Infection to Anxiety: A Sequential Model Linking Latent Toxoplasmosis to Psychological Distress via Health and Stress

Scandinavian Journal of Psychology, Volume 67, Issue 4, Page 1026-1043, August 2026.
ABSTRACT Identifying the drivers of chronic stress is crucial for understanding its impact on mental health. Latent toxoplasmosis, a widespread parasitic infection, has been linked to various psychological changes. The Stress‐Coping Hypothesis proposes that at least some of these changes are consequences of chronic stress arising from the infection's ...
Jaroslav Flegr, Ashkan Latifi, Šárka Kaňková   +2 more
wiley   +1 more source

Retinitis pigmentosa and congenital toxoplasmosis: A rare coexistence

Indian Journal of Ophthalmology, 2007
We describe a previously unreported co-existence of retinitis pigmentosa and congenital toxoplasmosis. An eight year old male presented to our center with complaints of decreased night vision.
Chhabra Manpreet, Prakash Gunjan, Vashisht Nagender, Garg S   +3 more
doaj  

Essential embryology for the Canadian pathologists’ assistant

Anatomical Sciences Education, Volume 19, Issue 7, Page 1134-1156, July 2026.
Abstract Pathologists' assistants (PAs) are pivotal in healthcare, conducting autopsies and examining tissues under a pathologist's guidance. Embryology knowledge is crucial for PAs to accurately assess anomalies and identify pathologies. Yet, it is often overlooked in academic PA training programs.
Samantha H. Nacci, William Tsui, Fang‐I Lu, Avrum I. Gotlieb, Danielle C. Bentley   +4 more
wiley   +1 more source

Congenital toxoplasmosis transmitted by human immunodeficiency-virus infected women

Brazilian Journal of Infectious Diseases
We report the occurrence of congenital toxoplasmosis in three infants born to HIV infected women who had high anti-toxoplasma IgG and negative IgM during pregnancy.
Kátia Martins Lopes de Azevedo, Sérgio Setúbal, Vania Gloria Silami Lopes, Luiz Antônio Bastos Camacho, Solange Artimos de Oliveira   +4 more
doaj   +1 more source

Toxoplasma gondii antibody profile in HIV-1-infected and uninfected pregnant women and the impact on congenital toxoplasmosis diagnosis in Rio de Janeiro, Brazil

Brazilian Journal of Infectious Diseases, 2012
Objective: Compare the anti-T. gondii IgG titer between HIV-1 infected and non HIV-1 infected pregnant women and report three cases of congenital toxoplasmosis resulting from reactivation of infection during pregnancy of HIV-1 infected women.
Márcia Antunes Fernandes, Giovanni Inácio Batista, Juliano da Costa Silveira Carlos, Ivete Martins Gomes, Kátia Martins Lopes de Azevedo, Sérgio Setúbal, Solange Artimos de Oliveira, Luis Guilhermo Coca Velarde, Claudete Aparecida Araújo Cardoso   +8 more
doaj   +1 more source