Results 71 to 80 of about 609,902 (236)

Disseminated and Congenital Toxoplasmosis in a Mother and Child With Activated PI3-Kinase δ Syndrome Type 2 (APDS2): Case Report and a Literature Review of Toxoplasma Infections in Primary Immunodeficiencies

Frontiers in Immunology, 2019
Phosphoinositide 3-kinase (PI3K) plays an integral role in lymphocyte function. Mutations in PIK3CD and PIK3R1, encoding the PI3K p110δ and p85α subunits, respectively, cause increased PI3K activity and result in immunodeficiency with immune ...
D. Karanovic, I. Michelow, A. Hayward, S. DeRavin, O. Delmonte, M. Grigg, A. K. Dobbs, J. Niemela, J. Stoddard, Zaid Alhinai, N. Rybak, N. Hernández, S. Pittaluga, S. Rosenzweig, G. Uzel, L. Notarangelo   +15 more
semanticscholar   +1 more source

Congenital Chagas Disease in the United States: Cost Savings Through Maternal Screening [PDF]

, 2018
Chagas disease, caused by Trypanosoma cruzi, is transmitted by insect vectors through transfusions, transplants, insect feces in food, and from mother to child during gestation.
Bialek, Stephanie R., Montgomery, Susan P., Perez-Zetune, Victoria, Stillwaggon, Eileen   +3 more
core   +2 more sources

Congenital toxoplasmosis as one phenocopy of North Carolina Macular Dystrophy (NCMD/MCDR1)

American Journal of Ophthalmology Case Reports, 2019
Purpose To highlight the striking similarities between the lesions of congenital toxoplasmosis (CT) and North Carolina Macular Dystrophy (NCMD) using multimodal imaging including spectral domain optical coherence tomography (SD-OCT).
K. Small, A. Vincent, Chelsey L. Knapper, F. Shaya   +3 more
semanticscholar   +1 more source

Early diagnosis of congenital toxoplasmosis in newborn infants using IgG subclasses against two Toxoplasma gondii recombinant proteins

Memorias do Instituto Oswaldo Cruz, 2012
The aim of this work was to evaluate the utility of ELISA-based testing of total IgG (IgGt) antibodies and its subclasses (IgG1, IgG2, IgG3 and IgG4) against soluble (STAg) and recombinant (rSAG1 and rMIC3) antigens of Toxoplasma gondii for diagnosing ...
Carlos Henryque de Souza e Silva, Gláucia Queiroz de Andrade, José Nélio Januário, Ana Carolina de Aguiar Vasconcelos Carneiro, Mariangela Carneiro, Daniel Vitor Vasconcelos-Santos, Ricardo Wagner de Almeida Vitor   +6 more
doaj   +1 more source

Toxoplasma effectors targeting host signaling and transcription [PDF]

, 2017
Early electron microscopy studies revealed the elaborate cellular features that define the unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) organelles and small, dense granules (GRAs), both of which are secreted during
Ajioka JA, Andrisani OM, Carruthers VB, Ceravolo IP, Deckert-Schlüter M, Dubey JP, Frenkel JK, Frenkel JK, Gazzinelli R, Gazzinelli RT, Gazzinelli RT, Goebel S, Honoré S, Levine ND, Luder CG, McCabe RE, McLeod R, McLeod R, Morisaki JH, Nash PB, Pfaff AW, Scharton-Kersten TM, Were SR, Yap GS   +23 more
core   +2 more sources

Evaluation of the level of awareness of congenital toxoplasmosis and associated practices among pregnant women and health workers in Tanzania's Temeke district in Dar es Salaam

African Health Sciences, 2019
Background Toxoplasmosis caused by the obligate intracellular coccidian protozoan Toxoplasma gondii (T. gondii) infects all warm-blooded animals including humans.
Onduru Gervas Onduru, S. Rumisha, Musso Munyeme, A. M. Phiri   +3 more
semanticscholar   +1 more source

Incidence of congenital toxoplasmosis in the city of Belém, state of Pará, northern Brazil, determined by a neonatal screening program: preliminary results

Revista da Sociedade Brasileira de Medicina Tropical, 2012
INTRODUCTION: The aim of this study was to determinate the incidence of congenital toxoplasmosis among a group of newborns (NBs) from Belém using neonatal screening.
Cléa Nazaré Carneiro Bichara, Giselle Acácia de Cristo Canto, Camila de Lima Tostes, Jofre Jacob da Silva Freitas, Ediclei Lima do Carmo, Marinete Marins Póvoa, Eliete da Costa Silveira   +6 more
doaj   +1 more source

A century of Toxoplasma gondii research [PDF]

, 2009
Toxoplasma gondii (Fig. 1) is a protozoan parasite that can be transmitted directly from cats to humans through faecal contamination of food, or indirectly from cats to livestock and then to humans through undercooked meat.
Henriquez, F.L., Roberts, Craig
core  

A latent ability to persist: differentiation in Toxoplasma gondii [PDF]

, 2018
A critical factor in the transmission and pathogenesis of Toxoplasma gondii is the ability to convert from an acute disease-causing, proliferative stage (tachyzoite), to a chronic, dormant stage (bradyzoite).
Jeffers, Victoria, Kim, Kami, Sullivan, William J., Jr., Tampaki, Zoi   +3 more
core   +1 more source

CONGENITAL TOXOPLASMOSIS: CLINICAL COURSE AND RESIDUAL OUTCOMES

Детские инфекции (Москва), 2015
We examined 69 infants with clinically manifested forms of congenital toxoplasmosis diagnosed in theStavropolregion in the period from 1992 to 2012. The clinical course was characterized by a predominance of severe forms of congenial toxoplasmosis, high ...
L. Yu. Barycheva, M. V. Golubeva, M. A. Kabulova, I. V. Kostornaya   +3 more
doaj   +1 more source