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Assessing the role of Ndel1 oligopeptidase activity in congenital Zika syndrome: Potential predictor of congenital syndrome endophenotype and treatment response

Journal of Neurochemistry, 2023
Maternal infections are among the main risk factors for cognitive impairments in the offspring. Zika virus (ZIKV) can be transmitted vertically, causing a set of heterogeneous birth defects, such as microcephaly, ventriculomegaly and corpus callosum ...
R. R. Christoff   +9 more
semanticscholar   +1 more source

Orthopaedic approach to the congenital Zika syndrome

International Orthopaedics, 2020
The aim of this study is to present a case series of patients with congenital Zika syndrome (CZS), giving special attention to the more relevant aspects for the paediatric orthopaedic surgeon.An analytical cross-sectional study was performed in a group of 47 patients affected by CZS with maternal Zika serology confirmation.
Marcos Almeida, Matos   +2 more
openaire   +2 more sources

Resilience in Mothers of Children with Congenital Zika Syndrome

Maternal and Child Health Journal, 2021
Resilience is a dynamic process influenced by life circumstances. This study evaluated the association between resilience and anxiety, depressive symptoms, and quality of life (QoL) of mothers of children with congenital Zika syndrome (CZS).This was a cross-sectional study including 31 mothers of children with CZS assisted in rehabilitation centers in ...
Victor Santana Santos   +6 more
openaire   +2 more sources

Glaucoma Workup in Congenital Zika Syndrome

Journal of Glaucoma, 2019
Purpose: The main aim of this study was to perform a glaucoma workup in infants with congenital Zika syndrome (CZS). Patient and Methods: This cross-sectional study included 188 eyes of 107 children (1.1±0.3 y; range, 0.3 to 1.8 y) with CZS.
Daniela R, de Oliveira   +7 more
openaire   +3 more sources

Experiences of children with congenital Zika syndrome while using motorized mobility: a qualitative study using the photovoice method

Disability and Rehabilitation: Assistive Technology
Aim The congenital Zika Syndrome (CZS) often leads to severe motor impairment in affected children, making independent walking unlikely. Early introduction of motorized mobility through ride-on cars has been recommended for young children with severe ...
Amanda Spínola Barreto   +8 more
semanticscholar   +1 more source

Neurodevelopmental outcomes in a cohort of children with congenital Zika syndrome at one and two years of age.

Child: Care, Health and Development, 2022
BACKGROUND Early child development is a critical stage of life that influences social, educational, and health outcomes worldwide. A few years after Zika epidemic, families of children born with congenital Zika syndrome (CZS) continue to face ...
F. J. Marques   +5 more
semanticscholar   +1 more source

Monitoring and Preventing Congenital Zika Syndrome

New England Journal of Medicine, 2016
The devastating fetal and infant outcomes associated with thalidomide use and rubella infection during pregnancy were key factors in the establishment of population-based surveillance for birth defects in the United States and globally to better monitor and address the effect of teratogens.1,2 This year, the recognition that Zika virus (ZIKV) infection
Margaret A, Honein, Denise J, Jamieson
openaire   +2 more sources

Molecular alterations in the extracellular matrix in the brains of newborns with congenital Zika syndrome

Science Signaling, 2020
Multiomics analysis reveals the changes that occur in the extracellular matrix in the brains of Zika virus–infected newborns. How Zika affects the extracellular matrix In some cases, Zika virus (ZIKV) infection during pregnancy leads to a series of ...
R. S. Aguiar   +31 more
semanticscholar   +1 more source

Multiomics Approach Reveals Serum Biomarker Candidates for Congenital Zika Syndrome.

Journal of Proteome Research
The Zika virus (ZIKV) can be vertically transmitted, causing congenital Zika syndrome (CZS) in fetuses. ZIKV infection in early gestational trimesters increases the chances of developing CZS.
Patrícia Sosa-Acosta   +7 more
semanticscholar   +1 more source

Epilepsy in children with Congenital Zika Syndrome: A systematic review and meta‐analysis

Epilepsia, 2021
To estimate the overall frequency of epilepsy in children with congenital Zika syndrome (CZS) and describe the profile of seizures and the response rate to anti‐epileptic treatment in this group of patients.
César Quadros Maia   +3 more
semanticscholar   +1 more source

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