Results 71 to 80 of about 12,164 (264)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Eogenetic caves in conglomerate: an example from Udin Boršt, Slovenia [PDF]
International Journal of Speleology, 2011 Udin Boršt is a karstified terrace of carbonate rock, which is of fluvioglacial origin, and is situated in the north-western part of Slovenia. There are 15 registered caves, which have been interpreted as caves in conglomerate, while karst of Udin Boršt ...
Lipar Matej, Ferk Mateja
doaj
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Aglomeraciones industriales y desarrollo económico. El caso de Hermosillo, 1998
Frontera Norte, 2006 This essay shows a methodological proposal for conglomerates analysis. Conglomerates and value chains analysis are applied to the automotive sector located at Hermosillo, Sonora, Mexico.
José Manuel Sánchez Gamboa +1 more
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Evaluation of Drillability of the Mahu Conglomerate Formation in Xinjiang, China
Energy Science & EngineeringThe conglomerate formation in China's Mahu oilfield is characterized by complex lithology, gravel development, and strong non‐homogeneity, resulting in difficult bit selection, low mechanical drilling speed, long drilling cycle, and difficulty in ...
Yun Xia +8 more
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Impact of Emotional Harassment on Firm’s Value
Frontiers in Psychology, 2018 The activities and consequences of workplace bullying and harassment have been widely explored in the literature but mainly studied within the scope of individuals or at the team level.
Yun Hyeong Choi +2 more
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Remote Sensing, 2017 On Kranjsko polje in central Slovenia, carbonate conglomerates have been dated to several Pleistocene glacial phases by relative dating based on the morphostratigrafic mapping and borehole data, and by paleomagnetic and 10Be analyses.
Teja Čeru, Ela Šegina, Andrej Gosar
doaj +1 more source