Results 121 to 130 of about 580 (224)
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Natural selection according to Darwin: cause or effect? [PDF]
Bradley B.
europepmc +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
A cross-sectional study of policies from American medical organizations about public communications from physicians in the digital age. [PDF]
Smith AJ +5 more
europepmc +1 more source
Mapping the International Geopolitical Agenda: Still National Conceptions of the Emerging European Crisi. [PDF]
Grasland C +3 more
europepmc +1 more source
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Consent and its discontents: the case of UK Biobank. [PDF]
Barn G.
europepmc +1 more source
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Stereotyping of the Russian Orthodox Church in Fake News in the Context of the COVID-19 Pandemic: Semiotic and Legal Analysis. [PDF]
Erokhina Y.
europepmc +1 more source
A conjecture on 3-vertex-critical graphs [PDF]
HuiQing LIU, Mei LU, ShunZhe ZHANG
openaire +1 more source

