Results 121 to 130 of about 345,370 (259)
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Toward a Geography of Architectural Criticism: Disciplinary Boundaries and Shared Territories (15)
, 2017 The multiple origins of modernist architecture criticism in the Belgian avant-garde magazine 7Arts (1922-1927) Irene Lund Faculty of Architecture, Université Libre de Bruxelles ; Katholieke Universiteit Leuven Between the 1920s and the end of the 1930s ...
Mapping Architectural Criticism
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Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Social Connectedness in Schizotypy: The Role of Cognitive and Affective Empathy. [PDF]
Behav Sci (Basel), 2022 Stinson J, Wolfe R, Spaulding W.
europepmc +1 more source
Architectural Criticism between Public Debate and Autonomous Discipline (2)
, 2016 Architectural centers: Mediation is the new Criticism Marcela Garcia Martinez University of Geneva Architecture centers are a new type of museum institution that emerged in Europe in the early 1980s.
Mapping Architectural Criticism
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Architectural Criticism between Public Debate and Autonomous Discipline (6)
, 2016 Mobilizing the Nation via Architectural Criticism : The Architectural Review “Outrage” and “Counterattack” Erdem Erten Associate Professor, Izmir Institute of Technology, Department of Architecture In June 1955, The Architectural Review’s special issue ...
Mapping Architectural Criticism
core +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Architectural Criticism between Public Debate and Autonomous Discipline (5)
, 2016 Dialogic Criticism Cedric Price’s Design Columns 1975-1999 Jim Njoo Associate Professor, École d’architecture de Paris-La Villette, TU Delft Department of Architecture For the radical British architect Cedric Price (1934-2003), architecture was above all
Mapping Architectural Criticism
core +1 more source