Results 131 to 140 of about 865,901 (361)
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Distance and de Sitter conjectures on the Swampland
Physics Letters B, 2019 Among Swampland conditions, the distance conjecture characterizes the geometry of scalar fields and the de Sitter conjecture constrains allowed potentials on it.
Hirosi Ooguri +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Textual Criticism of Mikhail Lermontov’s Poem “Valerik” (1840)
Научный диалогThe focus of this study lies in the editorial distortions present in the scientific editions of Lermontov’s works concerning the poem “Valerik” and the necessity of reconstructing a definitive text in accordance with the author’s intent. The objective of
I. A. Kiseleva, K. A. Potashova
doaj +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Statistical approaches and the Bekenstein bound conjecture in Schwarzschild black holes
, 2022 Éverton M. C. Abreu, Jorge Ananias Neto
openalex +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
, 2012 Fr\'ed\'eric Meunier's question about a multicolored Sperner lemma is addressed, leaving the question of connectivity for the color hypergraphs of such a multicolored simplex.
Babson, Eric
core
On Traces, Clues, and Fiction: Carlo Ginzburg and the Practice of Archaeology
Open ArchaeologyIn recent years, archaeological research has relied on large datasets, both temporally and geographically, with some archaeologists discussing that there should be a shift towards a more scientific form of conducting archaeological research called ...
Ribeiro Artur
doaj +1 more source