Results 151 to 160 of about 846,626 (359)

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

On a Conjecture of Matsushita

open access: yesInternational Mathematics Research Notices, 2015
We prove a weak version of a conjecture of Matsushita saying that for a Lagrangian fibration on a hyper-Kaehler manifold $X$, the moduli map for the fibers is either generically of maximal rank or constant. Assuming the base is smooth and $b_2(X)- (X)\geq5$, we prove the conjecture for a very general deformation of $X$ with constant N ron-Severi ...
L. Van Geemen, C. Voisin
openaire   +4 more sources

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

On a conjecture of Fomin [PDF]

open access: yesProceedings of the American Mathematical Society, 1962
Recently P. R. Halmos [5] mentioned a question raised by S. V. Fomin as to whether it follows that two measure preserving transformations are conjugate if they are unitarily equivalent and possess the same entropy. The purpose of this work is to concoct a counterexample to this conjecture.
openaire   +2 more sources

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

Second-order counterexample to the discrete-time Kalman conjecture

open access: yesEuropean Control Conference, 2015
In this paper, the discrete-time Kalman conjecture is shown to be false for systems of order two and above. Counterexamples are constructed. This contrasts with continuoustime domain systems where the Kalman conjecture is true for third-order systems.
J. Carrasco, W. Heath, M. Sen
semanticscholar   +1 more source

The cytochrome oxidase defect in ISC‐depleted yeast is caused by impaired iron–sulfur cluster maturation of the mitoribosome assembly factor Rsm22

open access: yesFEBS Letters, EarlyView.
The yeast mitoribosome assembly factor Rsm22 contains a [4Fe‐4S] cluster that is matured by the mitochondrial iron–sulfur cluster assembly (ISC) machinery. Defects in ISC components result in impaired mitochondrial protein synthesis due to a mitoribosome assembly defect.
Ulrich Mühlenhoff   +4 more
wiley   +1 more source

A note on nowhere-zero 3-flow and Z_3-connectivity

open access: yes, 2014
There are many major open problems in integer flow theory, such as Tutte's 3-flow conjecture that every 4-edge-connected graph admits a nowhere-zero 3-flow, Jaeger et al.'s conjecture that every 5-edge-connected graph is $Z_3$-connected and Kochol's ...
Chen, Fuyuan, Ning, Bo
core   +1 more source

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