Results 151 to 160 of about 871,047 (310)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
On surjective morphisms to abelian varieties and a generalization of the Iitaka conjecture [PDF]
, 2023 Fanjun Meng
openalex +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
On the Kudla-Rapoport conjecture for unitary Shimura varieties with maximal parahoric level structure at unramified primes [PDF]
, 2023 Sungyoon Cho, He Qiao, Zhe Zhang
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
A holographic derivation of the weak gravity conjecture [PDF]
, 2019 Miguel Montero
openalex +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
On Green and Green-Lazarfeld conjectures for simple coverings of algebraic curves
Le Matematiche, 2010 Let X be a smooth genus g curve equipped with a simple morphism f: X -> C, where C is either the projective line or more generally any smooth curve whose gonality is computed by finitely many pencils.
Edoardo Ballico, Claudio Fontanari
doaj
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Crouzeix's conjecture, compressions of shifts, and classes of nilpotent matrices
Concrete OperatorsThis article studies the level set Crouzeix (LSC) conjecture, which is a weak version of Crouzeix’s conjecture that applies to finite compressions of the shift.
Bickel Kelly +4 more
doaj +1 more source