Results 151 to 160 of about 865,901 (361)
22 pages, published version, abstract added in ...
Lacey, Michael, Thiele, Christoph
openaire +2 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Lang's Height Conjecture and Szpiro's Conjecture
It is known that Szpiro's conjecture, or equivalently the ABC-conjecture, implies Lang's conjecture giving a uniform lower bound for the canonical height of nontorsion points on elliptic curves. In this note we show that a significantly weaker version of Szpiro's conjecture, which we call "prime-depleted," suffices to prove Lang's conjecture.
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
A note on Fröberg's conjecture for forms of equal degrees [PDF]
Gleb Nenashev
openalex +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
On the superlinear Lazer-McKenna conjecture: the non-homogeneous case [PDF]
E. N. Dancer, Sanjiban Santra
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This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Gamma conjecture via mirror symmetry [PDF]
Sergey Galkin, Hiroshi Iritani
openalex +1 more source

